SP140 (NM_001278453) Human Untagged Clone

CAT#: SC337379

SP140 (untagged) - Human SP140 nuclear body protein (SP140), transcript variant 5

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SP140
• Synonyms: LYSP100; LYSP100-A; LYSP100-B
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001278453, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCCCAGCAGGGCCAGCAGGGGCAGATGGCAAGTGGAGACAGCAATCTCAACTTCAGGATGGTCGCAG
  AGATCCAGAACGTAGAGGGTCAGAACCTGCAGGAGCAGGTTTGCCCTGAGCCCATTTTCAGGTTCTTCAG
  AGAAAACAAGGTGGAGATTGCAAGTGCAATAACAAGGCCATTTCCTTTCCTTATGGGCCTCCGAGACCGC
  TCCTTCATCTCCGAGCAGATGTATGAACATTTTCAAGAAGCTTTTAGAAACCTGGTCCCAGTGACAAGAG
  TGATGTATTGTGTACTCAGTGAACTGGAGAAGACATTTGGCTGGTCACATCTGGAAGCATTGTTCAGCAG
  GATTAACCTGATGGCCTATCCTGATTTAAACGAGATTTACAGAAGCTTCCAGAATGTATGCTATGAACAC
  TCACCTCTCCAAATGAATAATGTAAACGATTTAGAAGATAGACCCAGATTACTACCATATGGTAAACAAG
  AGAACAGCAATGCCTGTCATGAAATGGATGATATAGCAGTGCCTCAGGAAGCCTTGAGCTCCTCGCCAAG
  GTGTGAGCCAGGTTTCTCTTCAGAGTCTTGTGAGCAGTTAGCTCTCCCAAAGGCTGGTGGAGGAGATGCT
  GAAGATGCACCCAGCCTACTACCAGTGTCCTGTAAACTTGCTATACAAATAGATGAAGGAGAATCAGAAG
  AAATGCCCAAGTTACTGCCTTATGATACAGAAGAGACCTTTGATCTAAAAACTCCCCAAGTCACTAATGA
  AGGAGAACCAGAGAAGGGGCTCTGTCTACTACCAGGTGAAGGAGAAGAGGGCAGTGATGACTGTTCGGAA
  ATGTGTGATGGAGAAGAGCGCCAGGAAGCCTCTAGCTCCCTAGCAAGACGTGGGTCAGTGTCTAGTGAAC
  TAGAAAATCACCCAATGAATGAAGAAGGAGAATCAGAAGAGCTTGCTTCTAGCCTGCTATATGATAATGT
  ACCAGGAGCGGAGCAATCAGCATATGAAAATGAGAAGTGTTCCTGTGTCATGTGTTTCTCAGAAGAGGTG
  CCAGGAAGCCCAGAAGCAAGGACGGAAAGTGATCAAGCGTGTGGCACAATGGATACTGTGGATATTGCAA
  ACAACTCCACTTTGGGAAAACCCAAGAGGAAAAGAAGAAAAAAGAGGGGGCATGGCTGGAGCAGAATGAG
  AATGAGAAGGCAGGAAAACAGCCAACAAAATGATAATAGCAAAGCCGACGGCCAGGTGGTCTCCAGTGAA
  AAGAAGGCGAACGTGAATCTGAAAGACCTTTCCAAGATTAGGGGGAGAAAGAGAGGCAAACCTGGAACCC
  GCTTCACTCAGAGTGACAGAGCTGCACAGAAAAGAGTCCGATCAAGAGCTTCAAGAAAGCACAAAGATGA
  AACTGTGGATTTTAAGGCTCCTTTGCTTCCAGTGACCTGTGGTGGGGTGAAGGGAATTTTACATAAGAAG
  AAATTGCAGCAAGGAATCTTGGTGAAGTGTATACAGACTGAGGATGGAAAATGGTTCACCCCCACGGAAT
  TTGAAATCAAAGGAGGCCATGCAAGATCAAAGAACTGGAGGCTGAGTGTGCGCTGTGGCGGGTGGCCCCT
  ACGATGGCTGATGGAGAATGGATTTCTGCCTGATCCTCCAAGAATACGTTACAGGAAAAAAAAGAGAATA
  CTGAAGTCTCAAAACAATAGCTCAGTTGACCCTTGTATGAGAAACCTGGATGAGTGTGAGGTGTGCCGGG
  ACGGAGGGGAGCTGTTCTGTTGCGACACTTGTTCAAGAGTCTTCCATGAGGACTGTCACATCCCGCCTGT
  GGAAGCTGAGAGGACCCCGTGGAATTGCATCTTCTGCAGGATGAAGGAGTCTCCGGGAAGCCAACAGTGT
  TGTCAGGAATCTGAGGTCCTGGAGAGGCAGATGTGTCCTGAGGAACAGTTGAAATGTGAGTTCCTCCTCT
  TGAAAGTCTATTGCTGTTCTGAGAGCTCCTTTTTTGCCAAGATTCCATACTATTATTATATTAGAGAGGC
  GTGTCAAGGCCTGAAGGAGCCCATGTGGTTGGATAAAATCAAGAAAAGGCTGAATGAGCACGGTTACCCC
  CAAGTGGAGGGGTTTGTACAAGACATGCGCCTCATCTTCCAGAACCACAGGGCCTCTTACAAGTACAAGG
  ATTTTGGCCAAATGGGATTTAGACTGGAGGCTGAGTTTGAGAAGAATTTCAAGGAAGTGTTTGCTATTCA
  GGAAACAAATGGGAACAATTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001278453
• ORF Size: 2262 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001278453.1, NP_001265382.1
• RefSeq Size: 2928
• RefSeq ORF: 2262
• Locus ID: 11262
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: This gene encodes a member of the SP100 family of proteins, which are share common domains including an N-terminal homogeneously staining region domain followed by a SP100/autoimmune regulator/NucP41/P75/deformed epidermal autoregulatory factor domain, a plant homeobox zinc finger, and a bromodomain. The encoded protein is interferon-inducible and is expressed at high levels in the nuclei of leukocytes. Variants of this gene have been associated with multiple sclerosis, Crohn's disease, and chronic lymphocytic leukemia. Alternative splicing results in multiple variants. [provided by RefSeq, Aug 2016]
  Transcript Variant: This variant (5) lacks three alternate in-frame exons and uses an alternate in-frame splice junction at the 3' end of an exon compared to variant 1. The resulting isoform (5) has the same N- and C-termini but is shorter compared to isoform 1.