SP140 (NM_001278452) Human Untagged Clone

CAT#: SC337498

SP140 (untagged) - Human SP140 nuclear body protein (SP140), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SP140
• Synonyms: LYSP100; LYSP100-A; LYSP100-B
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001278452, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCCCAGCAGGGCCAGCAGGGGCAGATGGCAAGTGGAGACAGCAATCTCAACTTCAGGATGGTCGCAG
  AGATCCAGAACGTAGAGGGTCAGAACCTGCAGGAGCAGGTTTGCCCTGAGCCCATTTTCAGGTTCTTCAG
  AGAAAACAAGGTGGAGATTGCAAGTGCAATAACAAGGCCATTTCCTTTCCTTATGGGCCTCCGAGACCGC
  TCCTTCATCTCCGAGCAGATGTATGAACATTTTCAAGAAGCTTTTAGAAACCTGGTCCCAGTGACAAGAG
  TGATGTATTGTGTACTCAGTGAACTGGAGAAGACATTTGGCTGGTCACATCTGGAAGCATTGTTCAGCAG
  GATTAACCTGATGGCCTATCCTGATTTAAACGAGATTTACAGAAGCTTCCAGAATGTATGCTATGAACAC
  TCACCTCTCCAAATGAATAATGTAAACGATTTAGAAGATAGACCCAGATTACTACCATATGGTAAACAAG
  AGAACAGCAATGCCTGTCATGAAATGGATGATATAGCAGTGCCTCAGGAAGCCTTGAGCTCCTCGCCAAG
  GTGTGAGCCAGGTTTCTCTTCAGAGTCTTGTGAGCAGTTAGCTCTCCCAAAGGCTGGTGGAGGAGATGCT
  GAAGATGCACCCAGCCTACTACCAGGTGGGGGAGTTCTAGAAAGCAACGGGATGATAGATGCGGCAAGGA
  CATACAGCACAGCACCAGGGGAGAAACAGGGAGAGGAGGAAGGCAGGAACAGTCCCAGAAAAAGAAACCA
  AGACAAGGAGAAGTACCAAGAGAGTCCAGAGGGAAGAGACAAAGAGACCTTTGATCTAAAAACTCCCCAA
  GTCACTAATGAAGGAGAACCAGAGAAGGGGCTCTGTCTACTACCAGGTGAAGGAGAAGAGGGCAGTGATG
  ACTGTTCAGAAATGTGTGATGGAGAAGAGCCCCAGGAAGCCTCTAGCTCCCTAGCAAGATGTGGGTCAGA
  GGGCAGTGATGACTGTTCGGAAATGTGTGATGGAGAAGAGCGCCAGGAAGCCTCTAGCTCCCTAGCAAGA
  CGTGGGTCAGTGTCTAGTGAACTAGAAAATCACCCAATGAATGAAGAAGGAGAATCAGAAGAGCTTGCTT
  CTAGCCTGCTATATGATAATGTACCAGGAGCGGAGCAATCAGCATATGAAAATGAGAAGTGTTCCTGTGT
  CATGTGTTTCTCAGAAGAGGTGCCAGGAAGCCCAGAAGCAAGGACGGAAAGTGATCAAGCGTGTGGCACA
  ATGGATACTGTGGATATTGCAAACAACTCCACTTTGGGAAAACCCAAGAGGAAAAGAAGAAAAAAGAGGG
  GGCATGGCTGGAGCAGAATGAGAATGAGAAGGCAGGAAAACAGCCAACAAAATGATAATAGCAAAGCCGA
  CGGCCAGGTGGTCTCCAGTGAAAAGAAGGCGAACGTGAATCTGAAAGACCTTTCCAAGATTAGGGGGAGA
  AAGAGAGGCAAACCTGGAACCCGCTTCACTCAGAGTGACAGAGCTGCACAGAAAAGAGTCCGATCAAGAG
  CTTCAAGAAAGCACAAAGATGAAACTGTGGATTTTAAGGCTCCTTTGCTTCCAGTGACCTGTGGTGGGGT
  GAAGGGAATTTTACATAAGAAGAAATTGCAGCAAGGAATCTTGGTGAAGTGTATACAGACTGAGGATGGA
  AAATGGTTCACCCCCACGGAATTTGAAATCAAAGGAGGCCATGCAAGATCAAAGAACTGGAGGCTGAGTG
  TGCGCTGTGGCGGGTGGCCCCTACGATGGCTGATGGAGAATGGATTTCTGCCTGATCCTCCAAGAATACG
  TTACAGGAAAAAAAAGAGAATACTGAAGTCTCAAAACAATAGCTCAGTTGACCCTTGTATGAGAAACCTG
  GATGAGTGTGAGGTGTGCCGGGACGGAGGGGAGCTGTTCTGTTGCGACACTTGTTCAAGAGTCTTCCATG
  AGGACTGTCACATCCCGCCTGTGGAAGCTGAGAGGACCCCGTGGAATTGCATCTTCTGCAGGATGAAGGA
  GTCTCCGGGAAGCCAACAGTGTTGTCAGGAATCTGAGGTCCTGGAGAGGCAGATGTGTCCTGAGGAACAG
  TTGAAATGTGAGTTCCTCCTCTTGAAAGTCTATTGCTGTTCTGAGAGCTCCTTTTTTGCCAAGATTCCAT
  ACTATTATTATATTAGAGAGGCGTGTCAAGGCCTGAAGGAGCCCATGTGGTTGGATAAAATCAAGAAAAG
  GCTGAATGAGCACGGTTACCCCCAAGTGGAGGGGTTTGTACAAGACATGCGCCTCATCTTCCAGAACCAC
  AGGGCCTCTTACAAGTACAAGGATTTTGGCCAAATGGGATTTAGACTGGAGGCTGAGTTTGAGAAGAATT
  TCAAGGAAGTGTTTGCTATTCAGGAAACAAATGGGAACAATTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001278452
• ORF Size: 2424 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001278452.1, NP_001265381.1
• RefSeq Size: 3090
• RefSeq ORF: 2424
• Locus ID: 11262
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: This gene encodes a member of the SP100 family of proteins, which are share common domains including an N-terminal homogeneously staining region domain followed by a SP100/autoimmune regulator/NucP41/P75/deformed epidermal autoregulatory factor domain, a plant homeobox zinc finger, and a bromodomain. The encoded protein is interferon-inducible and is expressed at high levels in the nuclei of leukocytes. Variants of this gene have been associated with multiple sclerosis, Crohn's disease, and chronic lymphocytic leukemia. Alternative splicing results in multiple variants. [provided by RefSeq, Aug 2016]
  Transcript Variant: This variant (4) lacks two alternate in-frame exons compared to variant 1. The resulting isoform (4) has the same N- and C-termini but is shorter compared to isoform 1.