SECISBP2 (NM_001282688) Human Untagged Clone

CAT#: SC337581

SECISBP2 (untagged) - Human SECIS binding protein 2 (SECISBP2), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SECISBP2
• Synonyms: SBP2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001282688, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGTCGGAGGGGCCGCGGGAGCCCGAAAGCGAGGGCATCAAGTTATCAGCAGATGTCAAACCATTTG
  TCCCCAGATTTGCCGGGCTCAATGTGGCATGGTTAGAGTCCTCAGAAGCATGTGTCTTCCCCAGCTCTGC
  AGCCACATACTATCCGTTTGTTCAGGAACCACCAGTGACAGAGCAGAAAATATATACTGAAGACATGGCC
  TTTGGAGCTTCAACTTTTCCACCTCAGTATTTATCTTCTGAGATAACTCTTCATCCATATGCCTATTCTC
  CTTATACCCTTGACTCCACACAGAATGTTTACTCAGTGCCTGGCTCCCAGTATCTTTATAACCAACCCAG
  TTGTTACCGAGGTTTTCAAACAGTGAAGCATCGAAATGAGAACACATGCCCTCTCCCACAAGAAATGAAA
  GCTCTGTTTAAGAAAACCTATGATGAGAAAAAAACGTATGATCAGCAAAAGTTTGACAGTGAAAGGGCTG
  ATGGAACTATATCATCTGAGATAAAATCAGCTAGAGGTTCACATCATTTGTCCATTTACGCTGAGAATAG
  TTTGAAATCAGATGGTTACCATAAGCGAACAGACAGGAAATCCAGAATCATTGCAAAAAATGTATCTACC
  TCCAAACCTGAGTTTGAATTTACCACACTGGACTTTCCTGAACTGCAAGGTGCAGAGAACAATATGTCAG
  AGATACAGAAGCAACCCAAGTGGGGACCTGTCCACTCTGTCTCTACCGACATTTCTCTTCTAAGAGAAGT
  AGTAAAACCAGCTGCAGTGTTATCAAAGGGTGAAATAGTGGTGAAAAATAACCCAAATGAATCTGTAACT
  GCTAATGCCGCTACCAATTCTCCTTCATGTACAAGAGAGTTATCTTGGACACCAATGGGTTATGTTGTTC
  GACAGACATTATCTACAGAACTGTCAGCAGCCCCTAAAAATGTTACTTCTATGATAAACTTAAAGACCAT
  TGCTTCATCAGCAGATCCTAAAAATGTTAGTATACCATCTTCTGAAGCTTTATCTTCGGATCCTTCCTAC
  AACAAAGAAAAACACATTATTCATCCTACCCAAAAGTCTAAAGCATCACAAGGTAGTGACCTTGAACAAA
  ATGAAGCCTCAAGAAAGAATAAGAAAAAGAAAGAAAAATCTACATCAAAATATGAAGTCCTGACAGTTCA
  AGAGCCTCCAAGGATTGAAGATGCCGAGGAATTTCCCAACCTGGCAGTTGCATCTGAAAGAAGAGACAGA
  ATAGAGACACCGAAATTTCAATCTAAGCAGCAGCCACAGGATAATTTTAAAAATAATGTAAAGAAGAGCC
  AGCTTCCAGTGCAGTTGGACTTGGGGGGCATGCTGACAGCCCTGGAGAAGAAGCAGCACTCTCAGCATGC
  AAAGCAGTCCTCCAAACCAGTGGTAGTCTCAGTTGGAGCAGTGCCAGTCCTTTCCAAAGAATGTGCATCA
  GGGGAGAGAGGCCGCCGCATGAGTCAAATGAAGACCCCGCACAATCCCTTGGACTCCAGCGCCCCACTGA
  TGAAGAAAGGGAAGCAGAGGGAGATCCCCAAGGCCAAGAAGCCAACCTCACTGAAGAAGATTATTTTGAA
  AGAACGGCAAGAGAGAAAGCAGCGTCTCCAAGAAAATGCTGTGAGTCCAGCTTTTACCAGTGATGACACA
  CAAGATGGAGAGAGTGGTGGTGATGACCAGTTTCCCGAGCAGGCAGAGCTGTCAGGGCCAGAGGGGATGG
  ACGAACTGATCTCCACTCCTTCGGTTGAGGACAAGTCTGAAGAGCCACCAGGCACAGAGCTCCAGAGGGA
  CACAGAGGCCTCCCACCTTGCTCCCAATCACACCACCTTCCCTAAGATCCACAGCCGCAGATTCAGGGAT
  TACTGCAGCCAGATGCTTAGTAAAGAAGTGGATGCTTGTGTTACCGACCTACTCAAAGAACTGGTCCGTT
  TCCAAGACCGTATGTACCAGAAAGATCCAGTCAAGGCCAAGACTAAACGTCGACTTGTGTTGGGGTTGAG
  GGAGGTTCTCAAACACCTGAAGCTCAAAAAACTGAAATGTGTCATTATTTCTCCCAACTGTGAGAAGATA
  CAGTCAAAAGGTGGGCTGGATGACACTTTGCACACAATTATTGATTATGCCTGTGAGCAGAACATTCCCT
  TTGTGTTTGCTCTCAACCGCAAAGCTCTGGGGCGCAGTTTGAATAAGGCAGTTCCTGTCAGTGTGGTGGG
  GATCTTCAGCTATGATGGGGCCCAGGATCAGTTCCACAAGATGGTTGAGCTGACAGTGGCGGCCCGACAG
  GCGTACAAGACCATGCTGGAGAATGTGCAGCAGGAGCTGGTGGGAGAGCCCAGGCCTCAGGCACCTCCCA
  GCCTACCCACACAGGGCCCCAGCTGCCCTGCAGAAGATGGCCCCCCAGCCCTGAAAGAAAAAGAAGAGCC
  ACACTACATTGAAATCTGGAAAAAACATCTGGAAGCATACAGTGGATGTACCCTGGAGCTAGAAGAATCC
  TTGGAGGCTTCAACCTCTCAAATGATGAATTTGAATTTATGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001282688
• ORF Size: 2562 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001282688.1, NP_001269617.1
• RefSeq Size: 3532
• RefSeq ORF: 2562
• Locus ID: 79048
• Gene Summary: The protein encoded by this gene is one of the essential components of the machinery involved in co-translational insertion of selenocysteine (Sec) into selenoproteins. Sec is encoded by the UGA codon, which normally signals translation termination. The recoding of UGA as Sec codon requires a Sec insertion sequence (SECIS) element; present in the 3' untranslated regions of eukaryotic selenoprotein mRNAs. This protein specifically binds to the SECIS element, which is stimulated by a Sec-specific translation elongation factor. Mutations in this gene have been associated with reduction in enzymatic activity of type II iodothyronine deiodinase (a selenoprotein) and abnormal thyroid hormone metabolism. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2017]
  Transcript Variant: This variant (2) uses an alternate in-frame acceptor splice site in the 5' coding region compared to variant 1. The encoded isoform (2) is 1 aa shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.