PEX1 (NM_001282678) Human Untagged Clone

CAT#: SC337833

PEX1 (untagged) - Human peroxisomal biogenesis factor 1 (PEX1), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PEX1
• Synonyms: HMLR1; PBD1A; PBD1B; ZWS; ZWS1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001282678, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGATGAAAGAACTTCAAACCAAGCAACTTCAGTCAAATACTGTGGGAATCACTGAATCTAATGAAAACG
  AGTCAGAGATTCCAGTTGACTCATCATCAGTAGCAAGTTTATGGACTATGATAGGAAGCATTTTTTCCTT
  TCAATCTGAGAAGAAACAAGAGACATCTTGGGGTTTAACTGAAATCAATGCATTCAAAAATATGCAGTCA
  AAGGTTGTTCCTCTAGACAATATTTTCAGAGTATGCAAATCTCAACCTCCTAGTATATATAACGCGTCAG
  CAACCTCTGTTTTTCATAAACACTGTGCCATTCATGTATTTCCATGGGACCAGGAATATTTTGATGTAGA
  GCCCAGCTTTACTGTGACATATGGAAAGCTAGTTAAGCTACTTTCTCCAAAGCAACAGCAAAGTAAAACA
  AAACAAAATGTGTTATCACCTGAAAAAGAGAAGCAGATGTCAGAGCCACTAGATCAAAAAAAAATTAGGT
  CAGATCATAATGAAGAAGATGAGAAGGCCTGTGTGCTACAAGTAGTCTGGAATGGACTTGAAGAATTGAA
  CAATGCCATCAAATATACCAAAAATGTAGAAGTTCTCCATCTTGGGAAAGTCTGGATTCCAGATGACCTG
  AGGAAGAGACTAAATATAGAAATGCATGCCGTAGTCAGGATAACTCCAGTGGAAGTTACCCCTAAAATTC
  CAAGATCTCTAAAGTTACAACCTAGAGAGAATTTACCTAAAGACATAAGTGAAGAAGACATAAAAACTGT
  ATTTTATTCATGGCTACAGCAGTCTACTACCACCATGCTTCCTTTGGTAATATCAGAGGAAGAATTTATT
  AAGCTGGAAACTAAAGATGGACTGAAGGAATTTTCTCTGAGTATAGTTCATTCTTGGGAAAAAGAAAAAG
  ATAAAAATATTTTTCTGTTGAGTCCCAATTTGCTGCAGAAGACTACAATACAAGTCCTTCTAGATCCTAT
  GGTAAAAGAAGAAAACAGTGAGGAAATTGACTTTATTCTTCCTTTTTTAAAGCTGAGCTCTTTGGGAGGA
  GTGAATTCCTTAGGCGTATCCTCCTTGGAGCACATCACTCACAGCCTCCTGGGACGCCCTTTGTCTCGGC
  AGCTGATGTCTCTTGTTGCAGGACTTAGGAATGGAGCTCTTTTACTCACAGGAGGAAAGGGAAGTGGAAA
  ATCAACTTTAGCCAAAGCAATCTGTAAAGAAGCATTTGACAAACTGGATGCCCATGTGGAGAGAGTTGAC
  TGTAAAGCTTTACGAGGAAAAAGGCTTGAAAACATACAAAAAACCCTAGAGGTGGCTTTCTCAGAGGCAG
  TGTGGATGCAGCCATCTGTTGTCCTGCTGGATGACCTTGACCTCATTGCTGGACTGCCTGCTGTCCCGGA
  ACATGAGCACAGTCCTGATGCGGTGCAGAGCCAGCGGCTTGCTCATGCTTTGAATGATATGATAAAAGAG
  TTTATCTCCATGGGAAGTTTGGTTGCACTGATTGCCACAAGTCAGTCTCAGCAATCTCTACATCCTTTAC
  TTGTTTCTGCTCAAGGAGTTCACATATTTCAGTGCGTCCAACACATTCAGCCTCCTAATCAGGAACAAAG
  ATGTGAAATTCTGTGTAATGTAATAAAAAATAAATTGGACTGTGATATAAACAAGTTCACCGATCTTGAC
  CTGCAGCATGTAGCTAAAGAAACTGGCGGGTTTGTGGCTAGAGATTTTACAGTACTTGTGGATCGAGCCA
  TACATTCTCGACTCTCTCGTCAGAGTATATCCACCAGAGAAAAATTAGTTTTAACAACATTGGACTTCCA
  AAAGGCTCTCCGCGGATTTCTTCCTGCGTCTTTGCGAAGTGTCAACCTGCATAAACCTAGAGACCTGGGT
  TGGGACAAGATTGGTGGGTTACATGAAGTTAGGCAGATACTCATGGATACTATCCAGTTACCTGCCAAGT
  ATCCAGAATTATTTGCAAACTTGCCCATACGACAAAGAACAGGAATACTGTTGTATGGTCCGCCTGGAAC
  AGGAAAAACCTTACTAGCTGGGGTAATTGCACGAGAGAGTAGAATGAATTTTATAAGTGTCAAGGGGCCA
  GAGTTACTCAGCAAATACATTGGAGCAAGTGAACAAGCTGTTCGGGATATTTTTATTAGAGCACAGGCTG
  CAAAGCCCTGCATTCTTTTCTTTGATGAATTTGAATCCATTGCTCCTCGGCGGGGTCATGATAATACAGG
  AGTTACAGACCGAGTAGTTAACCAGTTGCTGACTCAGTTGGATGGAGTAGAAGGCTTACAGGGTGTTTAT
  GTATTGGCTGCTACTAGTCGCCCTGACTTGATTGACCCTGCCCTGCTTAGGCCTGGTCGACTAGATAAAT
  GTGTATACTGTCCTCCTCCTGATCAGGTGTCACGTCTTGAAATTTTAAATGTCCTCAGTGACTCTCTACC
  TCTGGCAGATGATGTTGACCTTCAGCATGTAGCATCAGTAACTGACTCCTTTACTGGAGCTGATCTGAAA
  GCTTTACTTTACAATGCCCAATTGGAGGCCTTACATGGAATGCTGCTCTCGAGTGGACTCCAGGATGGAA
  GTTCCAGCTCTGATAGTGACCTAAGTCTGTCTTCAATGGTCTTTCTTAACCATAGCAGTGGCTCTGACGA
  TTCAGCTGGAGATGGAGAATGTGGCTTAGATCAGTCCCTTGTTTCTTTAGAGATGTCCGAGATCCTTCCA
  GATGAATCAAAATTCAATATGTACCGGCTCTACTTTGGAAGCTCTTATGAATCAGAACTTGGAAATGGAA
  CCTCTTCTGATTTGAGCTCACAATGTCTCTCTGCACCAAGCTCCATGACTCAGGATTTGCCTGGAGTTCC
  TGGGAAAGACCAGTTGTTTTCACAGCCTCCAGTGTTAAGGACAGCTTCACAAGAGGGTTGCCAAGAACTT
  ACACAAGAACAAAGAGATCAACTGAGGGCAGATATCAGTATTATCAAAGGCAGATACCGGAGCCAAAGTG
  GAGAGGACGAATCCATGAACCAACCAGGACCAATCAAAACCAGACTGGCTATTAGTCAGTCACATTTAAT
  GACTGCACTTGGTCACACAAGACCATCCATTAGTGAAGATGACTGGAAGAATTTTGCTGAGCTATATGAA
  AGCTTTCAAAATCCAAAGAGGAGAAAAAATCAAAGTGGAACAATGTTTCGACCTGGACAGAAAGTAACTT
  TAGCATAA
  
  
• Restriction Sites: SgfI-RsrII
• ACCN: NM_001282678
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001282678.1, NP_001269607.1
• RefSeq Size: 4427 bp
• RefSeq ORF: 3228 bp
• Locus ID: 5189
• Cytogenetics: 7q21.2
• Protein Families: Druggable Genome
• Gene Summary: 'This gene encodes a member of the AAA ATPase family, a large group of ATPases associated with diverse cellular activities. This protein is cytoplasmic but is often anchored to a peroxisomal membrane where it forms a heteromeric complex and plays a role in the import of proteins into peroxisomes and peroxisome biogenesis. Mutations in this gene have been associated with complementation group 1 peroxisomal disorders such as neonatal adrenoleukodystrophy, infantile Refsum disease, and Zellweger syndrome. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013]'
  Transcript Variant: This variant (3) uses an alternate donor splice site in the 5' region, which results in translation initiation from an in-frame downstream start codon, compared to variant 1. The resulting isoform (3) has a shorter N-terminus compared to isoform 1.