PEX1 (NM_001282677) Human Untagged Clone

CAT#: SC337950

PEX1 (untagged) - Human peroxisomal biogenesis factor 1 (PEX1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PEX1
• Synonyms: HMLR1; PBD1A; PBD1B; ZWS; ZWS1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001282677, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTGGGGCAGCGATCGCCTGGCGGGTGCTGGGGGAGGCGGGGCGGCAGTGACTGTGGCCTTCACCAACG
  CTCGCGACTGCTTCCTCCACCTGCCGCGGCGTCTCGTGGCCCAGCTGCATCTGCTGCAGAATCAAGCTAT
  AGAAGTGGTCTGGAGTCACCAGCCTGCATTCTTGAGCTGGGTGGAAGGCAGGCATTTTAGTGATCAAGGT
  GAAAATGTGGCTGAAATTAACAGACAAGTTGGTCAAAAACTTGGACTCTCAAATGGGGGACAGGTATTTC
  TCAAGCCATGTTCCCATGTGGTATCTTGTCAACAAGTTGAGGTGGAACCCCTCTCAGCAGATGATTGGGA
  GATACTGGAGCTGCATGCTGTTTCCCTTGAACAACATCTTCTAGATCAAATTCGAATAGTTTTTCCAAAA
  GCCATTTTTCCTGTTTGGGTTGATCAACAAACGTACATATTTATCCAAATTGTTGCACTAATACCAGCTG
  CCTCTTATGGAAGGCTGGAAACTGACACCAAACTCCTTATTCAGCCAAAGACACGCCGAGCCAAAGAGAA
  TACATTTTCAAAAGCTGATGCTGAATATAAAAAACTTCATAGTTATGGAAGAGACCAGAAAGGAATGATG
  AAAGAACTTCAAACCAAGCAACTTCAGTCAAATACTGTGGGAATCACTGAATCTAATGAAAACGAGTCAG
  AGATTCCAGTTGACTCATCATCAGTAGCAAGTTTATGGACTATGATAGGAAGCATTTTTTCCTTTCAATC
  TGAGAAGAAACAAGAGACATCTTGGGGTTTAACTGAAATCAATGCATTCAAAAATATGCAGTCAAAGGTT
  GTTCCTCTAGACAATATTTTCAGAGTATGCAAATCTCAACCTCCTAGTATATATAACGCGTCAGCAACCT
  CTGTTTTTCATAAACACTGTGCCATTCATGTATTTCCATGGGACCAGGAATATTTTGATGTAGAGCCCAG
  CTTTACTGTGACATATGGAAAGCTAGTTAAGCTACTTTCTCCAAAGCAACAGCAAAGTAAAACAAAACAA
  AATGTGTTATCACCTGAAAAAGAGAAGCAGATGTCAGAGCCACTAGATCAAAAAAAAATTAGGTCAGATC
  ATAATGAAGAAGATGAGAAGGCCTGTGTGCTACAAGTAGTCTGGAATGGACTTGAAGAATTGAACAATGC
  CATCAAATATACCAAAAATGTAGAAGTTCTCCATCTTGGGAAAGTCTGGATTCCAGATGACCTGAGGAAG
  AGACTAAATATAGAAATGCATGCCGTAGTCAGGATAACTCCAGTGGAAGTTACCCCTAAAATTCCAAGAT
  CTCTAAAGTTACAACCTAGAGAGAATTTACCTAAAGACATAAGTGAAGAAGACATAAAAACTGTATTTTA
  TTCATGGCTACAGCAGTCTACTACCACCATGCTTCCTTTGGTAATATCAGAGGAAGAATTTATTAAGCTG
  GAAACTAAAGATGGACTGAAGGAATTTTCTCTGAGTATAGTTCATTCTTGGGAAAAAGAAAAAGATAAAA
  ATATTTTTCTGTTGAGTCCCAATTTGCTGCAGAAGACTACAATACAAGTCCTTCTAGATCCTATGGTAAA
  AGAAGAAAACAGTGAGGAAATTGACTTTATTCTTCCTTTTTTAAAGCTGAGCTCTTTGGGAGGAGTGAAT
  TCCTTAGGCGTATCCTCCTTGGAGCACATCACTCACAGCCTCCTGGGACGCCCTTTGTCTCGGCAGCTGA
  TGTCTCTTGTTGCAGGACTTAGGAATGGAGCTCTTTTACTCACAGGAGGAAAGGGAAGTGGAAAATCAAC
  TTTAGCCAAAGCAATCTGTAAAGAAGCATTTGACAAACTGGATGCCCATGTGGAGAGAGTTGACTGTAAA
  GCTTTACGAGCTTTGAATGATATGATAAAAGAGTTTATCTCCATGGGAAGTTTGGTTGCACTGATTGCCA
  CAAGTCAGTCTCAGCAATCTCTACATCCTTTACTTGTTTCTGCTCAAGGAGTTCACATATTTCAGTGCGT
  CCAACACATTCAGCCTCCTAATCAGGAACAAAGATGTGAAATTCTGTGTAATGTAATAAAAAATAAATTG
  GACTGTGATATAAACAAGTTCACCGATCTTGACCTGCAGCATGTAGCTAAAGAAACTGGCGGGTTTGTGG
  CTAGAGATTTTACAGTACTTGTGGATCGAGCCATACATTCTCGACTCTCTCGTCAGAGTATATCCACCAG
  AGAAAAATTAGTTTTAACAACATTGGACTTCCAAAAGGCTCTCCGCGGATTTCTTCCTGCGTCTTTGCGA
  AGTGTCAACCTGCATAAACCTAGAGACCTGGGTTGGGACAAGATTGGTGGGTTACATGAAGTTAGGCAGA
  TACTCATGGATACTATCCAGTTACCTGCCAAGTATCCAGAATTATTTGCAAACTTGCCCATACGACAAAG
  AACAGGAATACTGTTGTATGGTCCGCCTGGAACAGGAAAAACCTTACTAGCTGGGGTAATTGCACGAGAG
  AGTAGAATGAATTTTATAAGTGTCAAGGGGCCAGAGTTACTCAGCAAATACATTGGAGCAAGTGAACAAG
  CTGTTCGGGATATTTTTATTAGAGCACAGGCTGCAAAGCCCTGCATTCTTTTCTTTGATGAATTTGAATC
  CATTGCTCCTCGGCGGGGTCATGATAATACAGGAGTTACAGACCGAGTAGTTAACCAGTTGCTGACTCAG
  TTGGATGGAGTAGAAGGCTTACAGGGTGTTTATGTATTGGCTGCTACTAGTCGCCCTGACTTGATTGACC
  CTGCCCTGCTTAGGCCTGGTCGACTAGATAAATGTGTATACTGTCCTCCTCCTGATCAGGTGTCACGTCT
  TGAAATTTTAAATGTCCTCAGTGACTCTCTACCTCTGGCAGATGATGTTGACCTTCAGCATGTAGCATCA
  GTAACTGACTCCTTTACTGGAGCTGATCTGAAAGCTTTACTTTACAATGCCCAATTGGAGGCCTTACATG
  GAATGCTGCTCTCGAGTGGACTCCAGGATGGAAGTTCCAGCTCTGATAGTGACCTAAGTCTGTCTTCAAT
  GGTCTTTCTTAACCATAGCAGTGGCTCTGACGATTCAGCTGGAGATGGAGAATGTGGCTTAGATCAGTCC
  CTTGTTTCTTTAGAGATGTCCGAGATCCTTCCAGATGAATCAAAATTCAATATGTACCGGCTCTACTTTG
  GAAGCTCTTATGAATCAGAACTTGGAAATGGAACCTCTTCTGATTTGAGCTCACAATGTCTCTCTGCACC
  AAGCTCCATGACTCAGGATTTGCCTGGAGTTCCTGGGAAAGACCAGTTGTTTTCACAGCCTCCAGTGTTA
  AGGACAGCTTCACAAGAGGGTTGCCAAGAACTTACACAAGAACAAAGAGATCAACTGAGGGCAGATATCA
  GTATTATCAAAGGCAGATACCGGAGCCAAAGTGGAGAGGACGAATCCATGAACCAACCAGGACCAATCAA
  AACCAGACTGGCTATTAGTCAGTCACATTTAATGACTGCACTTGGTCACACAAGACCATCCATTAGTGAA
  GATGACTGGAAGAATTTTGCTGAGCTATATGAAAGCTTTCAAAATCCAAAGAGGAGAAAAAATCAAAGTG
  GAACAATGTTTCGACCTGGACAGAAAGTAACTTTAGCATAA
  
  
• Restriction Sites: AscI-RsrII
• ACCN: NM_001282677
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001282677.1, NP_001269606.1
• RefSeq Size: 4221 bp
• RefSeq ORF: 3681 bp
• Locus ID: 5189
• Cytogenetics: 7q21.2
• Protein Families: Druggable Genome
• Gene Summary: 'This gene encodes a member of the AAA ATPase family, a large group of ATPases associated with diverse cellular activities. This protein is cytoplasmic but is often anchored to a peroxisomal membrane where it forms a heteromeric complex and plays a role in the import of proteins into peroxisomes and peroxisome biogenesis. Mutations in this gene have been associated with complementation group 1 peroxisomal disorders such as neonatal adrenoleukodystrophy, infantile Refsum disease, and Zellweger syndrome. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013]'
  Transcript Variant: This variant (2) is missing an in-frame coding exon compared to variant 1. The resulting shorter isoform (2) lacks an internal protein segment compared to isoform 1.