PIK3C2G (NM_001288774) Human Untagged Clone

CAT#: SC337976

PIK3C2G (untagged) - Human phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma (PIK3C2G), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PIK3C2G
• Synonyms: PI3K-C2-gamma; PI3K-C2GAMMA
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001288774, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCAGAAGAATATAGAGGTTGTTCCATTCAGCTAGTGGAAGTACCTCAAAGCAGCAATACGAGTCTGG
  CCTCTTTTTGCAACAAAGTAAAAAAAATCAGAGAAAGATATCATGCAGCTGATGTTAATTTCAATTCTGG
  GAAGATCTGGAGCACTACTACAGCATTTCCGTATCAGCTCTTTTCTAAGACCAAGTTTAATATACATATT
  TTTATTGATAACTCAACACAACCTCTTCATTTTATGCCATGTGCTAATTATCTTGTCAAAGATCTAATTG
  CAGAAATTCTGCATTTTTGCACAAATGACCAGCTACTCCCCAAAGATCATATTCTAAGTGTATGTGGCTC
  TGAAGAATTTTTACAAAACGACCACTGTTTGGGGAGCCACAAAATGTTTCAAAAAGATAAATCTGTTATT
  CAGCTCCACCTGCAGAAAAGTAGGGAAGCTCCAGGAAAGCTATCTCGAAAGCATGAAGAGGACCACAGTC
  AGTTTTATCTGAATCAACTTCTAGAATTTATGCATATTTGGAAAGTATCCAGACAATGTCTCTTAACACT
  CATCAGAAAATATGACTTCCACCTGAAATACCTATTGAAAACCCAGGAAAACGTGTATAATATTATTGAA
  GAAGTTAAAAAAATATGCAGTGTTCTAGGGTGTGTGGAAACCAAACAAATTACAGATGCAGTAAATGAAC
  TAAGTCTAATTCTTCAGAGAAAAGGAGAGAATTTTTATCAAAGTTCAGAGACTTCAGCAAAAGGCTTGAT
  AGAGAAGGTAACAACTGAACTATCCACATCCATCTACCAGCTAATCAATGTCTACTGTAACAGCTTTTAT
  GCAGATTTTCAGCCTGTAAATGTACCTAGATGCACTTCCTATCTAAATCCCGGGCTTCCTTCCCACCTCA
  GCTTCACAGTGTATGCAGCACACAACATTCCAGAAACCTGGGTGCACAGCTACAAAGCGTTTTCTTTTAC
  CTGTTGGCTTACATATGCTGGAAAGAAGCTGTGCCAAGTGAGAAACTACAGAAATATTCCAGACAAGAAA
  TTATTTTTTTTCTTGGTCAACTGGAATGAAACGATCAATTTTCCCCTTGAAATAAAGTCACTTCCAAGGG
  AATCCATGCTCACTGTAAAACTGTTTGGGATTGCCTGTGCAACCAACAATGCAAATTTACTGGCGTGGAC
  TTGTCTTCCACTGTTTCCAAAAGAAAAATCCATTCTCGGGTCTATGCTGTTCAGCATGACATTACAGAGT
  GAGCCTCCCGTAGAAATGATAACTCCAGGAGTGTGGGATGTAAGTCAGCCATCCCCGGTGACCCTGCAGA
  TTGATTTTCCAGCTACTGGGTGGGAGTATATGAAACCTGATTCTGAAGAGAATAGAAGTAATCTTGAAGA
  GCCACTAAAGGAGTGTATAAAACATATTGCCAGACTTTCACAGAAACAGACTCCCCTACTACTCTCTGAA
  GAAAAGAAAAGATATTTATGGTTTTATCGCTTCTACTGCAATAATGAAAACTGCTCCCTTCCTTTAGTCC
  TGGGTAGTGCCCCTGGATGGGATGAAAGGACTGTTTCAGAAATGCATACCATTTTGAGAAGATGGACATT
  TTCTCAACCTTTAGAGGCTCTTGGGCTTTTGACTTCCAGTTTTCCAGATCAAGAAATTCGTAAAGTGGCA
  GTTCAACAATTAGACAACCTCTTGAATGATGAACTACTGGAATATCTCCCACAGCTAGTTCAGGCTGTCA
  AGTTTGAATGGAACCTTGAGAGTCCTTTAGTGCAACTTCTACTCCACCGCTCCTTGCAGAGCATCCAGGT
  TGCCCATCGTCTTTACTGGCTGCTAAAAAATGCAGAAAATGAAGCTTATTTTAAAAGCTGGTATCAGAAG
  CTACTAGCTGCTCTCCAATTCTGTGCAGGTAAAGCCTTGAATGATGAGTTTTCCAAGGAGCAGAAACTTA
  TCAAAATTCTGGGAGATATTGGGGAAAGAGTCAAGTCTGCCAGTGACCATCAAAGACAGGAGGTACTGAA
  GAAAGAAATTGGCAGACTAGAAGAGTTCTTTCAAGATGTAAATACTTGTCATCTTCCTCTGAACCCTGCC
  CTATGTATAAAAGGGATTGATCACGATGCATGTTCATATTTTACATCTAATGCTTTGCCATTGAAGATTA
  CTTTCATCAATGCTAATCCGATGGGCAAAAACATCAGCATTATTTTTAAGGCTGGAGATGATCTTCGTCA
  GGATATGCTTGTTCTGCAGCTTATTCAAGTGATGGACAATATTTGGCTGCAGGAAGGCTTGGATATGCAA
  ATGATCATTTATAGATGTCTATCCACAGGAAAAGACCAAGGATTGGTGCAGATGGTACCTGATGCTGTGA
  CCCTAGCAAAGATTCATCGCCATTCTGGACTGATAGGACCATTGAAAGAAAATACAATTAAAAAGTGGTT
  CAGTCAGCACAACCACTTAAAGGCAGATTATGAAAAGGCCTTGAGGAACTTTTTCTACTCCTGTGCTGGC
  TGGTGTGTGGTAACATTCATCCTGGGAGTATGTGACCGTCACAATGATAATATCATGCTGACAAAGTCGG
  GCCACATGTTTCATATTGACTTTGGAAAATTCTTAGGTCATGCACAAACATTTGGAGGGATAAAAAGGGA
  CCGAGCTCCTTTCATTTTTACTTCAGAGATGGAATACTTTATTACAGAGGGTGGGAAAAACCCACAGCAT
  TTTCAAGATTTTGTGGAACTTTGCTGTCGTGCTTATAATATTATCAGAAAGCACAGCCAACTGCTCTTGA
  ACCTGCTGGAAATGATGCTGTATGCAGGACTGCCTGAGCTAAGTGGAATTCAAGACCTGAAATATGTGTA
  TAATAATCTTCGTCCACAAGACACAGACCTGGAAGCAACAAGTCATTTTACCAAGAAAATAAAGGAAAGT
  CTGGAGTGTTTCCCTGTTAAATTGAATAACTTGATCCACACACTTGCACAAATGTCAGCCATAAGCCCTG
  CCAAATCTACTTCACAGACTTTTCCTCAGGAATCCTGTTTGCTGAGTACAACTAGGTCGATTGAAAGAGC
  AACAATTTTAGGGTTCAGCAAGAAATCCAGTAATCTGTATCTGATCCAGGTGACACACAGCAACAACGAA
  ACAAGCCTGACAGAAAAATCATTTGAGCAGTTTTCAAAACTTCACAGCCAACTTCAGAAGCAGTTTGCAT
  CACTGACTCTCCCAGAGTTTCCTCATTGGTGGCACCTACCTTTTACAAATTCAGATCACAGAAGATTCAG
  AGATCTAAATCATTACATGGAACAGATATTAAATGTATCACATGAAGTTACAAACAGTGATTGTGTACTT
  AGCTTTTTCCTCTCTGAGGCTGTGCAACAAACAGTTGAAGAATCATCACCTGTGTACCTAGGTGAGAAGT
  TTCCAGACAAGAAGCCTAAGGTGCAGTTAGTCATATCCTACGAGGATGTGAAGCTGACCATACTAGTGAA
  ACACATGAAAAACATTCATCTCCCAGATGGCTCTGCGCCCAGTGCACATGTTGAATTTTATCTTTTACCA
  TATCCCAGTGAAGTTCGTAGGAGGAAAACAAAATCTGTTCCAAAATGTACGGACCCCACTTACAATGAAA
  TTGTAGTATATGATGAAGTCACAGAGCTCCAAGGACATGTCTTAATGCTTATTGTGAAGAGTAAAACTGT
  ATTTGTGGGAGCAATTAACATCCGACTCTGTAGTGTCCCACTCGATAAAGAAAAATGGTATCCATTAGGA
  AACAGTATAATTTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001288774
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001288774.1, NP_001275703.1
• RefSeq Size: 4964 bp
• RefSeq ORF: 3795 bp
• Locus ID: 5288
• Cytogenetics: 12p12.3
• Protein Families: Druggable Genome
• Protein Pathways: Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system
• Gene Summary: 'The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. This gene may play a role in several diseases, including type II diabetes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]'
  Transcript Variant: This variant (2) uses an alternate splice site in the 5' coding region, which results in the use of an alternate start codon and a frameshift, compared to variant 1. The encoded isoform (2) has a shorter and distinct N-terminus, compared to isoform 1.