KDM6A (NM_001291418) Human Untagged Clone

CAT#: SC338002

KDM6A (untagged) - Human lysine (K)-specific demethylase 6A (KDM6A), transcript variant 5

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KDM6A
• Synonyms: bA386N14.2; KABUK2; UTX
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001291418, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAAATCCTGCGGAGTGTCGCTCGCTACCGCCGCCGCTGCCGCCGCCGCTTTCGGTGATGAGGAAAAGA
  AAATGGCGGCGGGAAAAGCGAGCGGCGAGAGCGAGGAGGCGTCCCCCAGCCTGACAGCCGAGGAGAGGGA
  GGCGCTCGGCGGACTGGACAGCCGCCTCTTTGGGTTCGTGAGATTTCATGAAGATGGCGCCAGGACGAAG
  GCCCTACTGGGCAAGGCTGTTCGCTGCTATGAATCTCTAATCTTAAAAGCTGAAGGAAAAGTGGAGTCTG
  ATTTCTTTTGTCAATTAGGTCACTTCAACCTCTTATTGGAAGATTATCCAAAAGCATTATCTGCATACCA
  GAGGTACTACAGTTTACAGTCTGACTACTGGAAGAATGCTGCCTTTTTATATGGTCTTGGTTTGGTCTAC
  TTCCATTATAATGCATTTCAGTGGGCAATTAAAGCATTTCAGGAGGTGCTTTATGTTGATCCCAGCTTTT
  GTCGAGCCAAGGAAATTCATTTACGACTTGGGCTTATGTTCAAAGTGAACACAGACTATGAGTCTAGTTT
  AAAGCATTTTCAGTTAGCTTTGGTTGACTGTAATCCCTGCACTTTGTCCAATGCTGAAATTCAATTTCAC
  ATTGCCCACTTATATGAAACCCAGAGGAAATATCATTCTGCAAAAGAAGCTTATGAACAACTTTTGCAGA
  CAGAGAATCTTTCTGCACAAGTAAAAGCAACTGTCTTACAACAGTTAGGTTGGATGCATCACACTGTAGA
  TCTCCTGGGAGATAAAGCCACCAAGGAAAGCTATGCTATTCAGTATCTCCAAAAGTCCTTGGAAGCAGAT
  CCTAATTCTGGCCAGTCCTGGTATTTCCTCGGAAGGTGCTATTCAAGTATTGGGAAAGTTCAGGATGCCT
  TTATATCTTACAGGCAGTCTATTGATAAATCAGAAGCAAGTGCAGATACATGGTGTTCAATAGGTGTGCT
  ATATCAGCAGCAAAATCAGCCCATGGATGCTTTACAGGCCTATATTTGTGCTGTACAATTGGACCATGGC
  CATGCTGCAGCCTGGATGGACCTAGGCACTCTCTATGAATCCTGCAACCAGCCTCAGGATGCCATTAAAT
  GCTACTTAAATGCAACTAGAAGCAAAAGTTGTAGTAATACCTCTGCACTTGCAGCACGAATTAAGTATTT
  ACAGAATACTTCTGACAATTGGAGTGGTGGACATGCTGTGTCACATCCTCCAGTACAGCAACAAGCTCAT
  TCATGGTGTTTGACACCACAGAAATTACAGATGAGACCAACAGGAGTTGCACAGGTACGATCTACTGGAA
  TTCCTAATGGGCCAACAGCTGACTCATCACTGCCTACAAACTCAGTCTCTGGCCAGCAGCCACAGCTTGC
  TCTGACCAGAGTGCCTAGCGTCTCTCAGCCTGGAGTCCGTCCTGCCTGCCCTGGGCAGCCTTTGGCCAAT
  GGACCCTTTTCTGCAGGCCATGTTCCCTGTAGCACATCAAGAACGCTGGGAAGTACAGACACTATTTTGA
  TAGGCAATAATCATATAACAGGAAGTGGAAGTAATGGAAACGTGCCTTACCTGCAGCGAAACGCACTCAC
  TCTACCTCATAACCGCACAAACCTGACCAGCAGCGCAGAGGAGCCGTGGAAAAACCAACTATCTAACTCC
  ACTCAGGGGCTTCACAAAGGTCAGAGTTCACATTCGGCAGGTCCTAATGGTGAACGACCTCTCTCTTCCA
  CTGGGCCTTCCCAGCATCTCCAGGCAGCTGGCTCTGGTATTCAGAATCAGAACGGACATCCCACCCTGCC
  TAGCAATTCAGTAACACAGGGGGCTGCTCTCAATCACCTCTCCTCTCACACTGCTACCTCAGGTGGACAA
  CAAGGCATTACCTTAACCAAAGAGAGCAAGCCTTCAGGAAACATATTGACGGTGCCTGAAACAAGCAGGC
  ACACTGGAGAGACACCTAACAGCACTGCCAGTGTCGAGGGACTTCCTAATCATGTCCATCAGATGACGGC
  AGATGCTGTTTGCAGTCCTAGCCATGGAGATTCTAAGTCACCAGGTTTACTAAGTTCAGACAATCCTCAG
  CTCTCTGCCTTGTTGATGGGAAAAGCCAATAACAATGTGGGTACTGGAACCTGTGACAAAGTCAATAACA
  TCCACCCAGCTGTTCATACAAAGACTGATAACTCTGTTGCCTCTTCACCATCTTCAGCCATTTCAACAGC
  AACACCTTCTCCAAAATCCACTGAGCAGACAACCACAAACAGTGTTACCAGCCTTAACAGCCCTCACAGT
  GGGCTACACACAATTAATGGAGAAGGGATGGAAGAATCTCAGAGCCCCATGAAAACAGATCTGCTTCTGG
  TTAACCACAAACCTAGTCCACAGATCATACCATCAATGTCTGTGTCCATATACCCCAGCTCAGCAGAAGT
  TCTGAAGGCATGCAGGAATCTAGGTAAAAATGGCTTATCTAACAGTAGCATTTTGTTGGATAAATGTCCA
  CCTCCAAGACCACCATCTTCACCATACCCTCCCTTGCCAAAGGACAAGTTGAATCCACCTACACCTAGTA
  TTTACTTGGAAAATAAACGTGATGCTTTCTTTCCTCCATTACATCAATTTTGTACAAATCCGAACAACCC
  TGTTACAGTAATACGTGGCCTTGCTGGAGCTCTTAAGTTAGACCTGGGACTTTTCTCTACTAAAACTTTG
  GTGGAAGCTAACAATGAACATATGGTAGAAGTGAGGACACAGTTGTTGCAGCCAGCAGATGAAAACTGGG
  ATCCCACTGGAACAAAGAAAATCTGGCATTGTGAAAGTAATAGATCTCATACTACAATTGCTAAATATGC
  ACAGTACCAGGCCTCCTCATTCCAGGAATCATTGAGAGAAGAAAATGAAAAAAGAAGTCATCATAAAGAC
  CACTCAGATAGTGAATCTACATCGTCAGATAATTCTGGGAGGAGGAGGAAAGGACCCTTTAAAACCATAA
  AGTTTGGGACCAATATTGACCTATCTGATGACAAAAAGTGGAAGTTGCAGCTACATGAGCTGACTAAACT
  TCCTGCTTTTGTGCGTGTCGTATCAGCAGGAAATCTTCTAAGCCATGTTGGTCATACCATATTGGGCATG
  AACACAGTTCAACTATACATGAAAGTTCCAGGGAGCAGAACACCAGGTCATCAGGAAAATAACAACTTCT
  GTTCAGTTAACATAAATATTGGCCCAGGTGACTGTGAATGGTTTGTTGTTCCTGAAGGTTACTGGGGTGT
  TCTGAATGACTTCTGTGAAAAAAATAATTTGAATTTCCTAATGGGTTCTTGGTGGCCCAATCTTGAAGAT
  CTTTATGAAGCAAATGTTCCAGTGTATAGGTTTATTCAGCGACCTGGAGATTTGGTCTGGATAAATGCAG
  GCACTGTTCATTGGGTTCAGGCTATTGGCTGGTGCAACAACATTGCTTGGAATGTTGGTCCACTTACAGC
  CTGCCAGTATAAATTGGCAGTGGAACGGTACGAATGGAACAAATTGCAAAGTGTGAAGTCAATAGTACCC
  ATGGTTCATCTTTCCTGGAATATGGCACGAAATATCAAGGTCTCAGATCCAAAGCTTTTTGAAATGATTA
  AGTATTGTCTTCTAAGAACTCTGAAGCAATGTCAGACATTGAGGGAAGCTCTCATTGCTGCAGGAAAAGA
  GATTATATGGCATGGGCGGACAAAAGAAGAACCAGCTCATTACTGTAGCATTTGTGAAGTGGAGGTTTTT
  GATCTGCTTTTTGTCACTAATGAGAGTAATTCACGAAAGACCTACATAGTACATTGCCAAGATTGTGCAC
  GAAAAACAAGCGGAAACTTGGAAAACTTTGTGGTGCTAGAACAGTACAAAATGGAGGACCTGATGCAAGT
  CTATGACCAATTTACATTAGCTCCTCCATTACCATCCGCCTCATCTTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001291418
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001291418.1, NP_001278347.1
• RefSeq Size: 5548 bp
• RefSeq ORF: 3969 bp
• Locus ID: 7403
• Cytogenetics: Xp11.3
• Gene Summary: 'This gene is located on the X chromosome and is the corresponding locus to a Y-linked gene which encodes a tetratricopeptide repeat (TPR) protein. The encoded protein of this gene contains a JmjC-domain and catalyzes the demethylation of tri/dimethylated histone H3. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2014]'
  Transcript Variant: This variant (5) lacks two consecutive in-frame exons and a single in-frame exon in the coding region, compared to variant 1. The resulting isoform (5) lacks two internal segments, compared to isoform 1.