PIK3C2G (NM_001288772) Human Untagged Clone

CAT#: SC338057

PIK3C2G (untagged) - Human phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma (PIK3C2G), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PIK3C2G
• Synonyms: PI3K-C2-gamma; PI3K-C2GAMMA
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001288772, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCATATTCTTGGCAAACGGATCCAAATCCTAATGAATCACACGAAAAGCAGTATGAACACCAAGAAT
  TTCTCTTTGTAAATCAACCCCATTCTTCTAGCCAAGTCAGTCTGGGTTTTGATCAGATAGTAGATGAGAT
  CAGTGGCAAAATTCCACACTACGAGAGTGAAATTGATGAAAACACCTTTTTTGTGCCCACTGCACCAAAA
  TGGGACTCAACAGGGCATTCATTAAATGAAGCACACCAAATATCCTTGAATGAATTCACTTCTAAAAGCC
  GTGAACTCTCCTGGCATCAAGTTAGCAAAGCACCAGCAATTGGTTTTAGTCCTTCTGTGTTACCAAAACC
  TCAAAATACGAATAAAGAATGCTCCTGGGGAAGCCCCATAGGAAAACATCATGGTGCTGATGATTCCAGA
  TTCAGTATTTTAGCTCCATCATTCACAAGTTTGGATAAAATTAATCTAGAGAAAGAATTAGAAAATGAAA
  ATCATAACTACCATATAGGATTTGAAAGTAGCATTCCTCCAACAAATTCATCCTTCTCAAGTGACTTCAT
  GCCGAAAGAAGAGAATAAAAGGAGTGGACATGTGAACATTGTGGAACCATCTTTGATGCTTTTGAAAGGC
  TCTCTTCAACCCGGAATGTGGGAAAGTACATGGCAGAAGAATATAGAGTCAATAGGTTGTTCCATTCAGC
  TAGTGGAAGTACCTCAAAGCAGCAATACGAGTCTGGCCTCTTTTTGCAACAAAGTAAAAAAAATCAGAGA
  AAGATATCATGCAGCTGATGTTAATTTCAATTCTGGGAAGATCTGGAGCACTACTACAGCATTTCCGTAT
  CAGCTCTTTTCTAAGACCAAGTTTAATATACATATTTTTATTGATAACTCAACACAACCTCTTCATTTTA
  TGCCATGTGCTAATTATCTTGTCAAAGATCTAATTGCAGAAATTCTGCATTTTTGCACAAATGACCAGCT
  ACTCCCCAAAGATCATATTCTAAGTGTATGTGGCTCTGAAGAATTTTTACAAAACGACCACTGTTTGGGG
  AGCCACAAAATGTTTCAAAAAGATAAATCTGTTATTCAGCTCCACCTGCAGAAAAGTAGGGAAGCTCCAG
  GAAAGCTATCTCGAAAGCATGAAGAGGACCACAGTCAGTTTTATCTGAATCAACTTCTAGAATTTATGCA
  TATTTGGAAAGTATCCAGACAATGTCTCTTAACACTCATCAGAAAATATGACTTCCACCTGAAATACCTA
  TTGAAAACCCAGGAAAACGTGTATAATATTATTGAAGAAGTTAAAAAAATATGCAGTGTTCTAGGGTGTG
  TGGAAACCAAACAAATTACAGATGCAGTAAATGAACTAAGTCTAATTCTTCAGAGAAAAGGAGAGAATTT
  TTATCAAAGTTCAGAGACTTCAGCAAAAGGCTTGATAGAGAAGGTAACAACTGAACTATCCACATCCATC
  TACCAGCTAATCAATGTCTACTGTAACAGCTTTTATGCAGATTTTCAGCCTGTAAATGTACCTAGATGCA
  CTTCCTATCTAAATCCCGGGCTTCCTTCCCACCTCAGCTTCACAGTGTATGCAGCACACAACATTCCAGA
  AACCTGGGTGCACAGCTACAAAGCGTTTTCTTTTACCTGTTGGCTTACATATGCTGGAAAGAAGCTGTGC
  CAAGTGAGAAACTACAGAAATATTCCAGACAAGAAATTATTTTTTTTCTTGGTCAACTGGAATGAAACGA
  TCAATTTTCCCCTTGAAATAAAGTCACTTCCAAGGGAATCCATGCTCACTGTAAAACTGTTTGGGATTGC
  CTGTGCAACCAACAATGCAAATTTACTGGCGTGGACTTGTCTTCCACTGTTTCCAAAAGAAAAATCCATT
  CTCGGGTCTATGCTGTTCAGCATGACATTACAGAGTGAGCCTCCCGTAGAAATGATAACTCCAGGAGTGT
  GGGATGTAAGTCAGCCATCCCCGGTGACCCTGCAGATTGATTTTCCAGCTACTGGGTGGGAGTATATGAA
  ACCTGATTCTGAAGAGAATAGAAGTAATCTTGAAGAGCCACTAAAGGAGTGTATAAAACATATTGCCAGA
  CTTTCACAGAAACAGACTCCCCTACTACTCTCTGAAGAAAAGAAAAGATATTTATGGTTTTATCGCTTCT
  ACTGCAATAATGAAAACTGCTCCCTTCCTTTAGTCCTGGGTAGTGCCCCTGGATGGGATGAAAGGACTGT
  TTCAGAAATGCATACCATTTTGAGAAGATGGACATTTTCTCAACCTTTAGAGGCTCTTGGGCTTTTGACT
  TCCAGTTTTCCAGATCAAGAAATTCGTAAAGTGGCAGTTCAACAATTAGACAACCTCTTGAATGATGAAC
  TACTGGAATATCTCCCACAGCTAGTTCAGGCTGTCAAGTTTGAATGGAACCTTGAGAGTCCTTTAGTGCA
  ACTTCTACTCCACCGCTCCTTGCAGAGCATCCAGGTTGCCCATCGTCTTTACTGGCTGCTAAAAAATGCA
  GAAAATGAAGCTTATTTTAAAAGCTGGTATCAGAAGCTACTAGCTGCTCTCCAATTCTGTGCAGGTAAAG
  CCTTGAATGATGAGTTTTCCAAGGAGCAGAAACTTATCAAAATTCTGGGAGATATTGGGGAAAGAGTCAA
  GTCTGCCAGTGACCATCAAAGACAGGAGGTACTGAAGAAAGAAATTGGCAGACTAGAAGAGTTCTTTCAA
  GATGTAAATACTTGTCATCTTCCTCTGAACCCTGCCCTATGTATAAAAGGGATTGATCACGATGCATGTT
  CATATTTTACATCTAATGCTTTGCCATTGAAGATTACTTTCATCAATGCTAATCCGATGGGCAAAAACAT
  CAGCATTATTTTTAAGGCTGGAGATGATCTTCGTCAGGATATGCTTGTTCTGCAGCTTATTCAAGTGATG
  GACAATATTTGGCTGCAGGAAGGCTTGGATATGCAAATGATCATTTATAGATGTCTATCCACAGGAAAAG
  ACCAAGGATTGGTGCAGATGGTACCTGATGCTGTGACCCTAGCAAAGATTCATCGCCATTCTGGACTGAT
  AGGACCATTGAAAGAAAATACAATTAAAAAGTGGTTCAGTCAGCACAACCACTTAAAGGCAGATTATGAA
  AAGGCCTTGAGGAACTTTTTCTACTCCTGTGCTGGCTGGTGTGTGGTAACATTCATCCTGGGAGTATGTG
  ACCGTCACAATGATAATATCATGCTGACAAAGTCGGGCCACATGTTTCATATTGACTTTGGAAAATTCTT
  AGGTCATGCACAAACATTTGGAGGGATAAAAAGGGACCGAGCTCCTTTCATTTTTACTTCAGAGATGGAA
  TACTTTATTACAGAGGGTGGGAAAAACCCACAGCATTTTCAAGATTTTGTGGAACTTTGCTGTCGTGCTT
  ATAATATTATCAGAAAGCACAGCCAACTGCTCTTGAACCTGCTGGAAATGATGCTGTATGCAGGACTGCC
  TGAGCTAAGTGGAATTCAAGACCTGAAATATGTGTATAATAATCTTCGTCCACAAGACACAGACCTGGAA
  GCAACAAGTCATTTTACCAAGAAAATAAAGGAAAGTCTGGAGTGTTTCCCTGTTAAATTGAATAACTTGA
  TCCACACACTTGCACAAATGTCAGCCATAAGCCCTGCCAAATCTACTTCACAGACTTTTCCTCAGGAATC
  CTGTTTGCTGAGTACAACTAGGTCGATTGAAAGAGCAACAATTTTAGGGTTCAGCAAGAAATCCAGTAAT
  CTGTATCTGATCCAGGTGACACACAGCAACAACGAAACAAGCCTGACAGAAAAATCATTTGAGCAGTTTT
  CAAAACTTCACAGCCAACTTCAGAAGCAGTTTGCATCACTGACTCTCCCAGAGTTTCCTCATTGGTGGCA
  CCTACCTTTTACAAATTCAGATCACAGAAGATTCAGAGATCTAAATCATTACATGGAACAGATATTAAAT
  GTATCACATGAAGTTACAAACAGTGATTGTGTACTTAGCTTTTTCCTCTCTGAGGCTGTGCAACAAACAG
  TTGAAGAATCATCACCTGTGTACCTAGGTGAGAAGTTTCCAGACAAGAAGCCTAAGGTGCAGTTAGTCAT
  ATCCTACGAGGATGTGAAGCTGACCATACTAGTGAAACACATGAAAAACATTCATCTCCCAGATGGCTCT
  GCGCCCAGTGCACATGTTGAATTTTATCTTTTACCATATCCCAGTGAAGTTCGTAGGAGGAAAACAAAAT
  CTGTTCCAAAATGTACGGACCCCACTTACAATGAAATTGTAGTATATGATGAAGTCACAGAGCTCCAAGG
  ACATGTCTTAATGCTTATTGTGAAGAGTAAAACTGTATTTGTGGGAGCAATTAACATCCGACTCTGTAGT
  GTCCCACTCGATAAAGAAAAATGGTATCCATTAGGAAACAGTATAATTTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001288772
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001288772.1, NP_001275701.1
• RefSeq Size: 4971 bp
• RefSeq ORF: 4461 bp
• Locus ID: 5288
• Cytogenetics: 12p12.3
• Protein Families: Druggable Genome
• Protein Pathways: Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system
• Gene Summary: 'The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. This gene may play a role in several diseases, including type II diabetes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]'
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).