Nance Horan Syndrome Protein (NHS) (NM_001291867) Human Untagged Clone

CAT#: SC338087

NHS (untagged) - Human Nance-Horan syndrome (congenital cataracts and dental anomalies) (NHS), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NHS
• Synonyms: CTRCT40; CXN; SCML1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001291867, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCCTTTCGCCAAGCGGATCGTGGAGCCGCAATGGCTGTGCAGGCAGCGGCGCCCTGCGCCCGGCCCAG
  CAGTGGACGCGAGCGGAGGCAGCGCTGAGCCGCCGCCGCCCTTGCAGCCGCCGGGCCGGAGGGACCTGGA
  CGAGGTCGAGGCGCCAGGGCCAGAGGAGCCAGCCCGCGCCGTCCCTGCACCTTCAGGGCTGCCACCGCCG
  CCGCCGCCACTGCCCGCGCCGGCCGACCAGACTCAGCCGCCGCACGGAGAGGCGTCCGTGGCTGGCGAGG
  AGAGCACGGCGGGGATCCCGGAGGCGGCGCCCGCAGCCGGCGAGGCGTCCTCGGCGGCGGCGGCGGCGGC
  CGTGCTGCTCATGCTGGACCTATGCGCGGTCAGCAACGCCGCTCTGGCCCGTGTCCTCCGGCAGCTCTCG
  GACGTGGCCCGGCACGCTTGCAGCCTCTTCCAGGAGCTCGAGAGCGACATCCAGCTCACCCACCGCCGCG
  TCTGGGCGCTGCAGGGCAAGCTCGGCGGCGTGCAGCGCGTCCTCAGCACGCTTGACCCTAAGCAGGAGGC
  AGTGCCCGTCTCCAACCTGGACATAGAGAGTAAGCTGAGTGTGTACTACCGCGCCCCGTGGCACCAGCAG
  CGCAACATCTTCCTCCCAGCCACAAGGCCACCCTGCGTGGAGGAGCTGCACCGCCACGCCCGGCAGAGCC
  TGCAAGCCCTGCGCAGAGAACACCGGAGCCGGAGCGATCGCCGAGAGCAAAGAGCAGCTGCCCCCCTTTC
  CATTGCAGCTCCTCCACTGCCAGCCTACCCTCCAGCTCACAGCCAGAGGAGGCGTGAGTTTAAGGACCGT
  CACTTTTTAACGTTTAACAGCACCCGTTCGCCCTCCCCCACTGAATGTTGCCACATGACCCCGTGGAGTA
  GAAAGTCCCATCCCCCAGAGGATGAAGATACAGATGTCATGTTAGGGCAGAGGCCGAAAAACCCAATACA
  CAATATCCCTTCCACACTGGACAAGCAGACCAACTGGAGCAAAGCACTACCTCTCCCGACGCCAGAGGAG
  AAGATGAAACAAGATGCCCAAGTGATTTCTTCTTGCATTATTCCCATCAATGTTACTGGAGTTGGCTTTG
  ACAGAGAGGCTAGTATACGCTGCTCTCTGGTTCATTCACAATCGGTACTACAGCGGAGACGAAAATTGAG
  GAGGAGGAAAACCATCTCGGGTATCCCCAGAAGAGTTCAACAAGAAATAGATTCTGATGAATCACCAGTG
  GCCAGGGAAAGGAATGTGATTGTGCACACAAACCCAGACCCCTCCAACACTGTCAATAGGATATCCGGAA
  CCAGGGACTCTGAGTGCCAAACCGAGGATATTCTGATTGCTGCCCCATCCAGAAGGAGAATCAGAGCTCA
  AAGGGGTCAAAGCATTGCAGCTTCCCTTTCTCATTCTGCTGGCAACATTTCTGCCCTAGCAGACAAAGGT
  GACACCATGTTTACTCCTGCAGTGAGCAGCCGCACAAGATCTCGGAGCCTTCCCCGGGAAGGTAATAGAG
  GTGGGGATGCTGAGCCCAAAGTTGGCGCTAAACCCTCAGCATATGAAGAGGGAGAGTCTTTTGTGGGTGA
  CCATGAAAGAACCCCTAATGATTTCAGTGAGGCTCCAAGCAGCCCGAGTGCCCAGGACCACCAGCCTACT
  TTGGGCCTGGCCTGCTCTCAACATCTTCACAGCCCCCAGCACAAATTAAGTGAGAGGGGAAGGTCACGTC
  TGTCCCGAATGGCTGCTGACTCTGGCAGCTGTGACATCTCCTCCAACTCAGACACGTTTGGGAGCCCCAT
  CCACTGCATCTCCACGGCTGGCGTCCTCCTTAGCAGCCACATGGACCAGAAAGATGACCACCAGTCATCC
  AGTGGCAACTGGAGTGGGAGCAGCTCCACGTGCCCCTCGCAGACCTCAGAAACCATCCCTCCTGCAGCTT
  CTCCTCCACTCACTGGCTCTTCACACTGTGACTCGGAGTTGTCACTAAACACAGCCCCTCATGCCAATGA
  GGATGCCAGTGTTTTCGTGACAGAGCAATACAATGACCACTTGGATAAAGTGAGAGGCCATCGGGCAAAC
  TCCTTTACCTCCACTGTTGCAGACCTGCTGGATGATCCCAACAACAGCAACACAAGTGACAGTGAGTGGA
  ATTACCTACACCACCACCATGATGCCTCCTGCCGCCAGGATTTTAGTCCTGAGCGTCCCAAGGCAGACAG
  CCTGGGCTGCCCAAGCTTCACAAGCATGGCCACTTATGACAGCTTTCTGGAAAAGTCTCCATCAGACAAA
  GCGGACACTAGCTCTCACTTTTCAGTAGACACGGAAGGATACTATACCTCCATGCACTTTGACTGTGGTC
  TCAAAGGTAATAAGAGCTATGTCTGTCACTATGCAGCCCTGGGCCCAGAGAATGGCCAGGGTGTAGGGGC
  TTCCCCTGGTCTTCCAGATTGTGCCTGGCAGGACTACTTAGACCACAAGAGGCAGGGAAGACCAAGCATC
  TCTTTCAGGAAACCAAAGGCAAAGCCGACCCCACCTAAACGTAGCTCATCATTGAGGAAGTCTGATGGAA
  ACGCAGATATTTCTGAGAAGAAAGAACCAAAGATAAGCAGTGGTCAGCACCTGCCTCACAGTTCCAGGGA
  AATGAAGCTGCCTCTTGATTTCGCCAACACGCCTTCTCGAATGGAAAACGCCAATCTTCCCACCAAGCAG
  GAACCTTCTTGGATAAACCAGAGTGAACAAGGCATTAAGGAACCTCAGTTAGATGCTTCGGATATTCCAC
  CATTCAAAGATGAAGTTGCCGAATCCACACACTATGCAGACCTCTGGCTCCTAAATGACTTGAAAACAAA
  TGATCCTTATAGATCTCTATCTAATTCAAGCACCGCTACGGGTACCACAGTCATTGAATGCATCAAATCT
  CCAGAGAGCTCTGAATCCCAAACATCACAATCAGAATCAAGAGCCACCACCCCATCTCTTCCTTCTGTTG
  ACAATGAGTTTAAACTGGCTTCACCAGAAAAGCTGGCTGGCTTGGCATCTCCATCAAGTGGCTATTCAAG
  CCAGTCTGAAACGCCAACATCCTCTTTCCCTACAGCTTTCTTTTCAGGTCCATTGTCTCCCGGAGGTAGC
  AAAAGAAAACCTAAAGTCCCAGAAAGAAAATCCTCACTACAGCAACCCTCTTTAAAAGATGGAACTATAT
  CACTGAGTAAAGACCTTGAACTTCCAATTATACCTCCTACCCATCTTGATCTAAGTGCTCTTCATAATGT
  CTTGAACAAACCATTCCACCACCGTCATCCACTGCATGTTTTTACTCATAATAAGCAGAACACAGTAGGA
  GAAACACTGAGGTCGAATCCTCCACCGTCCCTTGCAATTACACCAACGATCCTGAAATCTGTTAACCTTA
  GGTCCATCAACAAGTCTGAAGAAGTTAAGCAAAAAGAAGAAAACAATACAGATCTCCCTTATTTAGAGGA
  AAGCACACTCACAACGGCTGCCTTGTCTCCAAGTAAGATTAGGCCGCATACAGCAAATAAATCAGTATCT
  CGTCAATACTCCACTGAAGACACCATACTGTCCTTTTTAGACTCTTCTGCAGTTGAGATGGGACCAGATA
  AACTACATTTAGAAAAAAACTCTACTTTTGATGTGAAGAATCGCTGCGATCCAGAAACCATAACATCAGC
  TGGTAGCAGTCTTCTAGATTCAAATGTCACAAAAGACCAAGTGCGTACAGAGACTGAGCCTATTCCAGAA
  AACACGCCAACCAAAAACTGTGCTTTTCCCACAGAAGGATTTCAGAGGGTCTCTGCTGCCCGCCCAAATG
  ATTTGGATGGTAAAATAATACAATATGGACCTGGTCCAGACGAAACTCTAGAACAGGTACAGAAGGCACC
  CTCTGCAGGTCTGGAGGAAGTTGCACAACCTGAATCTGTGGATGTAATCACATCTCAGTCAGACTCACCA
  ACTAGAGCAACAGATGTAAGCAATCAATTTAAGCATCAATTTGTTATGAGCCGCCACCATGACAAAGTGC
  CTGGTACTATCAGCTATGAATCGGAGATAACATCTGTAAATTCATTCCCTGAAAAATGTTCCAAGCAGGA
  AAATATTGCTTCAGGTATTTCAGCCAAAAGTGCCTCTGATAACAGCAAAGCAGAGGAGACCCAAGGAAAT
  GTGGATGAGGCTTCATTGAAAGAATCATCACCGAGTGATGACTCCATCATTTCACCACTTAGTGAAGACT
  CCCAAGCTGAAGCAGAGGGTGTGTTCGTGTCTCCAAACAAACCTCGAACAACTGAGGATTTATTTGCAGT
  CATTCACAGATCCAAGAGGAAAGTACTTGGAAGAAAAGATTCCGGGGACATGTCTGTTCGAAGCAAATCG
  AGAGCTCCCCTCAGCAGTAGCAGCAGCAGCGCCAGTTCCATCACTTCACCCAGCAGTAATGTGACAACCC
  CCAACAGCCAGAGGTCTCCTGGTCTCATATACCGAAATGCCAAAAAGTCCAACACATCCAATGAAGAGTT
  TAAGCTGTTACTGCTCAAGAAAGGCAGTCGCTCAGATTCTAGTTACCGCATGTCTGCCACTGAGATCCTG
  AAGAGCCCCATACTGCCCAAACCTCCTGGGGAGCTCACAGCAGAGTCCCCTCAGAGCACCGATGATGCCC
  ATCAGGGGTCACAAGGGGCTGAGGCATTGTCCCCACTCTCTCCATGCTCCCCACGAGTTAATGCAGAAGG
  CTTTTCCTCGAAGAGCTTTGCCACCTCAGCATCAGCAAGGGTTGGACGTTCTCGGGCCCCTCCTGCAGCC
  AGCAGCAGCCGCTACAGTGTCCGCTGCCGGCTGTACAATACGCCCATGCAGGCAATCTCCGAGGGAGAGA
  CGGAAAATTCTGACGGGAGCCCACATGACGACCGTTCCTCCCAGAGTTCAACATAG
  
  
• Restriction Sites: AscI-MluI
• ACCN: NM_001291867
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001291867.1, NP_001278796.1
• RefSeq Size: 8839 bp
• RefSeq ORF: 4956 bp
• Locus ID: 4810
• Cytogenetics: Xp22.2-p22.13
• Gene Summary: 'This gene encodes a protein containing four conserved nuclear localization signals. The encoded protein functions in eye, tooth, craniofacial and brain development, and it can regulate actin remodeling and cell morphology. Mutations in this gene have been shown to cause Nance-Horan syndrome, and also X-linked cataract-40. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2014]'
  Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (3).