XRN1 (NM_001282857) Human Untagged Clone

CAT#: SC338095

XRN1 (untagged) - Human 5'-3' exoribonuclease 1 (XRN1), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: XRN1
• Synonyms: SEP1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001282857, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGGAGTCCCCAAGTTTTACAGATGGATCTCAGAGCGGTATCCCTGTCTCAGCGAAGTGGTGAAAGAGC
  ATCAGATTCCTGAATTTGACAACTTGTACCTGGATATGAATGGAATTATACATCAGTGCTCCCATCCTAA
  TGATGATGATGTTCACTTTAGAATTTCAGATGATAAAATCTTTACTGATATTTTTCACTACCTGGAGGTG
  TTGTTTCGCATTATTAAACCCAGGAAAGTGTTCTTTATGGCTGTAGATGGTGTGGCTCCTCGAGCAAAAA
  TGAACCAGCAGCGTGGGAGGCGTTTTAGGTCAGCAAAGGAGGCAGAAGACAAAATTAAAAAGGCAATAGA
  GAAGGGAGAAACTCTTCCTACAGAGGCCAGATTTGATTCCAACTGTATCACACCAGGAACTGAATTTATG
  GCCAGGTTACATGAACATCTGAAGTATTTTGTAAATATGAAAATTTCCACAGACAAGTCATGGCAAGGAG
  TTACCATCTACTTCTCAGGCCATGAGACTCCTGGAGAAGGAGAGCATAAAATCATGGAATTTATCAGATC
  CGAGAAAGCAAAGCCAGATCATGATCCAAACACCAGACACTGTCTTTATGGTTTAGATGCTGACTTGATT
  ATGCTTGGATTAACAAGTCATGAGGCACATTTTTCTCTCTTAAGAGAAGAAGTTCGATTTGGTGGCAAAA
  AAACACAACGGGTATGTGCTCCAGAAGAAACTACATTTCACCTTCTACACTTGTCTTTAATGAGAGAGTA
  TATTGACTATGAGTTTTCAGTATTAAAAGAAAAGATCACATTTAAATATGATATTGAAAGGATAATAGAT
  GATTGGATTTTGATGGGGTTTCTTGTTGGTAATGATTTTATCCCTCATCTACCTCATTTACATATTAATC
  ATGATGCACTGCCTCTTCTTTATGGAACATATGTTACCATCCTGCCAGAACTTGGGGGTTATATTAATGA
  AAGTGGGCACCTCAACTTACCTCGATTTGAGAAATACCTTGTGAAACTATCAGATTTTGATCGGGAGCAC
  TTCAGTGAAGTTTTTGTGGACCTAAAATGGTTTGAAAGCAAAGTTGGTAACAAGTACCTCAATGAAGCAG
  CAGGTGTCGCAGCAGAAGAAGCCAGGAACTACAAGGAAAAGAAAAAGTTAAAGGGCCAGGAAAATTCTCT
  GTGTTGGACTGCTTTAGACAAAAATGAAGGCGAAATGATAACTTCTAAGGATAATTTAGAAGATGAGACT
  GAAGATGATGACCTATTTGAAACTGAGTTTAGACAATATAAAAGAACATATTACATGACGAAGATGGGGG
  TTGACGTAGTATCTGATGACTTTCTGGCTGATCAAGCTGCATGTTATGTTCAGGCAATACAGTGGATTTT
  GCACTATTACTATCATGGAGTTCAGTCCTGGAGCTGGTATTATCCTTATCATTATGCACCTTTCCTGTCT
  GATATACACAACATCAGTACACTCAAAATCCATTTTGAACTAGGAAAACCTTTTAAGCCATTTGAACAGC
  TTCTTGCTGTACTTCCAGCAGCCAGCAAAAATTTACTTCCTGCATGCTACCAGCATTTGATGACCAATGA
  AGACTCACCAATTATAGAATATTACCCACCTGATTTTAAAACTGACCTAAATGGGAAACAACAGGAATGG
  GAAGCTGTGGTGTTAATCCCTTTTATTGATGAGAAGCGATTATTGGAAGCCATGGAGACATGTAACCACT
  CCCTCAAAAAGGAAGAGAGGAAAAGAAACCAACATAGTGAGTGCCTAATGTGCTGGTATGATAGAGACAC
  AGAGTTTATCTATCCTTCTCCATGGCCAGAAAAGTTCCCTGCCATAGAACGATGTTGTACAAGGTATAAA
  ATAATATCCTTAGATGCTTGGCGTGTAGACATAAACAAAAACAAAATAACCAGAATTGACCAGAAAGCAT
  TATATTTCTGTGGATTTCCTACTCTGAAACACATCAGACACAAATTTTTTTTGAAGAAAAGTGGTGTTCA
  AGTATTCCAGCAAAGCAGTCGTGGAGAAAACATGATGTTGGAAATCTTAGTGGATGCAGAATCAGATGAA
  CTTACCGTAGAAAATGTAGCTTCATCAGTGCTTGGAAAATCTGTCTTTGTTAATTGGCCTCACCTTGAGG
  AAGCTAGAGTCGTGGCTGTATCAGATGGAGAAACTAAGTTTTACTTGGAAGAACCTCCAGGAACACAGAA
  GCTTTATTCAGGAAGAACTGCCCCACCATCTAAAGTGGTTCATCTTGGAGATAAAGAACAATCTAACTGG
  GCAAAAGAAGTACAAGGAATTTCAGAACACTACCTGAGAAGAAAAGGAATAATAATAAATGAAACATCTG
  CAGTTGTGTATGCTCAGTTACTCACAGGTCGTAAATATCAAATAAATCAAAATGGTGAAGTTCGTCTAGA
  GAAACAGTGGTCAAAACAAGTTGTTCCTTTTGTTTATCAAACTATTGTCAAGGACATCCGAGCTTTCGAC
  TCCCGTTTCTCCAATATCAAAACATTGGATGATTTGTTTCCTCTGAGAAGTATGGTCTTTATGCTGGGAA
  CTCCCTATTATGGCTGCACTGGAGAAGTTCAGGATTCAGGTGATGTGATTACAGAAGGTAGGATTCGTGT
  GATTTTCAGCATTCCATGTGAACCCAATCTTGATGCTTTAATACAGAACCAGCATAAATATTCTATAAAG
  TACAACCCAGGATATGTGTTGGCCAGTCGCCTTGGAGTGAGTGGATACCTTGTTTCAAGGTTTACAGGAA
  GTATTTTTATTGGAAGAGGATCTAGGAGAAACCCTCATGGAGACCATAAAGCAAATGTGGGTTTAAATCT
  CAAATTCAACAAGAAAAATGAGGAGGTACCTGGATATACTAAGAAAGTTGGAAGTGAATGGATGTATTCA
  TCTGCAGCAGAACAACTTCTGGCAGAGTACTTAGAGAGAGCTCCAGAACTATTTAGTTATATAGCCAAAA
  ATAGCCAAGAGGATGTGTTCTATGAAGATGACATTTGGCCTGGAGAAAATGAGAATGGTGCTGAAAAAGT
  TCAAGAAATTATTACTTGGCTAAAAGGACATCCTGTCAGTACTTTATCTCGTTCTTCTTGTGATTTACAA
  ATTCTGGATGCAGCTATTGTTGAGAAAATTGAGGAAGAAGTCGAAAAGTGCAAGCAAAGAAAGAATAATA
  AGAAGGTGCGAGTAACAGTGAAACCCCATTTGCTATACAGACCTTTAGAACAGCAACATGGAGTCATTCC
  TGATCGGGATGCAGAATTTTGTCTTTTTGACCGTGTTGTAAATGTGAGAGAAAACTTCTCAGTTCCAGTT
  GGCCTTCGAGGCACCATCATAGGAATAAAAGGAGCTAATAGAGAAGCCGATGTACTATTTGAAGTATTAT
  TTGATGAAGAATTTCCTGGAGGGTTAACAATAAGATGCTCACCTGGTAGAGGTTATCGACTGCCAACAAG
  TGCCTTGGTGAACCTTTCTCATGGGAGTCGCTCTGAAACTGGAAATCAGAAGTTGACAGCCATCGTAAAA
  CCACAACCAGCTGTACATCAACATAGCTCAAGTTCATCAGTTTCCTCTGGGCATTTGGGAGCCCTCAACC
  ATTCCCCTCAATCACTTTTTGTTCCTACTCAAGTACCTACTAAAGATGATGATGAATTCTGCAACATTTG
  GCAGTCCTTACAGGGATCTGGAAAGATGCAATACTTTCAGCCAACTATACAAGAGAAGGGTGCAGTTCTA
  CCTCAAGAAATAAGCCAAGTAAATCAACATCATAAATCTGGCTTTAATGACAACAGTGTTAAATATCAGC
  AAAGAAAACATGACCCTCACAGAAAATTTAAAGAAGAGTGTAAGAGTCCTAAAGCTGAGTGTTGGTCCCA
  AAAAATGTCCAATAAGCAGCCTAACTCTGGAATTGAGAACTTTTTAGCATCTTTGAATATCTCCAAAGAA
  AATGAAGTACAGTCATCTCATCATGGGGAGCCTCCAAGTGAAGAGCATTTGTCACCACAGTCATTTGCCA
  TGAAGGGAACACGGATGCTTAAAGAAATTCTAAAAATTGATGGCTCTAACACTGTGGACCATAAGAATGA
  AATCAAACAGATTGCTAATGAAATCCCTGTTTCCTCTAACAGAAGAGATGAATATGGATTACCCTCTCAG
  CCTAAACAAAATAAGAAATTAGCATCTTATATGAACAAGCCTCACAGTGCTAATGAGTACCATAATGTTC
  AGTCTATGGACAATATGTGTTGGCCTGCCCCCAGCCAGATCCCTCCTGTATCCACACCAGTAACTGAACT
  TTCTCGAATTTGTTCCCTTGTTGGAATGCCACAACCTGATTTCTCCTTTCTTAGGATGCCACAGACAATG
  ACCGTTTGCCAAGTAAAATTATCTAATGGCTTACTGGTACATGGGCCACAGTGCCACTCTGAAAATGAAG
  CCAAAGAGAAAGCTGCACTTTTTGCTTTACAACAGTTGGGCTCCTTAGGCATGAATTTCCCTTTGCCTTC
  ACAAGTATTTGCAAATTATCCTTCAGCTGTACCACCTGGAACCATTCCTCCAGCCTTTCCCCCACCTACT
  GCTAATATAATGCCTTCGTCGTCTCATCTCTTTGGCTCAATGCCATGGGGACCATCGGTGCCAGTTCCTG
  GGAAGCCCTTCCATCATACTTTATATTCTGGGACCATGCCCATGGCTGGGGGAATACCAGGGGGTGTGCA
  CAATCAGTTTATACCTCTGCAGGTTACTAAAAAAAGGGTTGCAAACAAAAAGAACTTTGAGAATAAGGAA
  GCCCAGAGTTCTCAAGCCACTCCAGTTCAGACTAGCCAGCCAGATTCTTCCAACATTGTCAAAGTAAGTC
  CACGGGAGAGCTCATCAGCTTCTTTGAAGTCCTCTCCGATTGCTCAACCTGCATCTTCTTTTCAAGTTGA
  AACTGCCTCTCAAGGCCATAGTATATCTCACCATAAGTCAACACCAATCTCTTCTTCAAGAAGAAAATCA
  AGAAAACTGGCTGTTAATTTTGGTGTTTCTAAACCTTCTGAGTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001282857
• ORF Size: 5085 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001282857.1, NP_001269786.1
• RefSeq Size: 10107
• RefSeq ORF: 5085
• Locus ID: 54464
• Protein Pathways: RNA degradation
• Gene Summary: This gene encodes a member of the 5'-3' exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts directly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
  Transcript Variant: This variant (3) lacks an in-frame exon in the 3' coding region, compared to variant 1. The encoded isoform (c) is shorter, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.