JMJD1C (NM_001282948) Human Untagged Clone

CAT#: SC338139

JMJD1C (untagged) - Human jumonji domain containing 1C (JMJD1C), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: JMJD1C
• Synonyms: KDM3C; TRIP-8; TRIP8
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001282948, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCAAGGTCCTTATTCCTTAAATGGATACAGAGTGAGAGTATATAGACAAGACTCTGCCACCCAGTGGT
  TTACTGGCATAATTACTCATCATGATCTCTTCACCCGCACCATGATCGTTATGAATGATCAGGTACTAGA
  ACCACAGAATGTCGATCCTTCTATGGTTCAAATGACCTTTCTAGATGATGTTGTTCACTCTTTGTTAAAA
  GGTGAAAATATTGGCATTACATCACGACGCAGGTCTCGTGCCAATCAAAACGTCAACGCTGTTCACAGCC
  ATTATACACGTGCCCAAGCAAATAGTCCCAGACCAGCAATGAACTCCCAAGCTGCTGTACCAAAACAGAA
  TACACACCAGCAACAGCAACAAAGAAGTATCCGTCCAAATAAGAGGAAGGGCTCAGATAGCAGTATACCA
  GATGAAGAGAAGATGAAGGAGGAAAAATATGATTATATATCACGAGGAGAAAATCCTAAAGGTAAAAACA
  AACACTTGATGAATAAAAGAAGGAAACCTGAGGAGGATGAAAAGAAACTAAATATGAAAAGACTTCGAAC
  TGACAATGTTTCAGACTTTTCTGAGAGCAGTGACTCAGAAAATTCAAATAAGAGAATAATAGATAATTCC
  TCAGAACAGAAGCCAGAGAATGAATTGAAAAATAAAAATACTTCAAAAATAAATGGAGAAGAAGGAAAAC
  CCCATAATAATGAGAAGGCAGGAGAAGAGACCCTAAAAAATAGCCAGCCTCCCTGGGATCAAATACAGGA
  AGATAAAAAACATGAAGAAGCAGAGAAGCGGAAGTCTGTTGACACTCAGCTTCAAGAAGATATGATTATT
  CATTCGTCAGAACAGTCCACAGTTTCTGATCATAATTCTAATGATTTACTTCCTCAGGAATGCAATATGG
  ATAAAACACATACCATGGAATTGCTACCAAAGGAGAAGTTTGTATCCAGACCACCCACACCAAAATGTGT
  TATTGATATTACAAATGACACTAATTTAGAAAAGGTGGCTCAGGAAAACTCAAGTACCTTTGGCCTTCAG
  ACACTTCAGAAAATGGATCCTAATGTTAGTGATTCAAAACACTCTATTGCAAATGCAAAATTCTTGGAAA
  CAGCAAAAAAAGATTCTGACCAGAGCTGGGTCAGTGATGTAGTTAAAGTGGATCTAACCCAATCAAGTGT
  TACAAATGCTTCTTCAGGAAATGATCACTTGAACATGGAAAAAGAGAAGTATGTCTCTTACATTTCTCCT
  TTAAGTGCAGTTTCTGTCATGGAAGATAAGCTGCATAAGCGAAGTCCACCTCCAGAGACTATAAAATCTA
  AACTTAATACTTCAGTAGATACTCACAAGATAAAATCCAGCCCATCACCTGAAGTTGTTAAACCCAAAAT
  AACTCATTCTCCTGATTCTGTAAAGTCTAAGGCCACTTATGTGAACAGCCAAGCTACTGGTGAAAGAAGA
  TTGGCAAATAAGATAGAACATGAGCTATCAAGATGCAGTTTTCATCCAATTCCTACTCGAAGCAGTACAT
  TAGAAACTACAAAGAGTCCTCTTATCATTGATAAAAATGAGCATTTTACAGTTTACAGAGATCCTGCACT
  TATTGGGTCAGAAACAGGAGCTAATCATATTTCACCTTTCCTAAGCCAGCATCCTTTTCCTCTTCACTCC
  TCATCTCATAGAACCTGTTTAAATCCAGGTACCCATCATCCTGCCTTAACTCCTGCACCCCATTTACTAG
  CCGGATCATCTAGTCAAACTCCATTACCTACCATTAACACTCATCCTCTGACTAGTGGTCCACACCATGC
  TGTTCATCACCCTCATTTACTTCCCACTGTGTTACCTGGAGTGCCTACTGCCTCCTTACTTGGTGGCCAC
  CCACGACTAGAGAGTGCTCATGCCAGCAGCTTGAGCCACTTAGCGCTAGCACACCAGCAACAACAACAGT
  TGTTACAGCACCAGTCACCTCATCTTCTTGGACAAGCCCATCCTTCTGCTTCATATAATCAGCTTGGACT
  TTATCCAATTATTTGGCAGTATCCAAATGGAACACATGCATACTCAGGACTTGGTTTGCCTTCTTCTAAG
  TGGGTTCACCCAGAAAATGCAGTTAATGCTGAAGCTTCATTAAGGAGGAATTCTCCCAGTCCTTGGCTAC
  ATCAGCCCACCCCTGTGACCTCAGCAGATGGTATTGGATTACTTAGTCACATTCCTGTCAGACCTTCCAG
  TGCAGAGCCTCATCGGCCTCTTAAAATTACAGCCCATTCCAGTCCACCATTGACAAAAACTTTAGTAGAT
  CATCATAAGGAAGAATTAGAAAGAAAAGCTTTTATGGAACCATTACGGTCTGTTGCATCCACATCAGCCA
  AAAATGACCTGGATCTAAATAGGTCACAGACTGGAAAAGATTGTCACTTACATAGGCATTTTGTGGATCC
  AGTATTAAATCAGTTACAGAGGCCACCCCAGGAGACTGGAGAGAGGTTAAACAAATACAAAGAGGAACAC
  CGTCGAATTCTTCAAGAAAGTATTGATGTTGCTCCCTTTACAACTAAAATCAAGGGACTTGAGGGTGAGA
  GAGAGAATTATTCCAGAGTGGCATCATCATCTTCCAGTCCTAAAAGCCATATCATCAAACAAGATATGGA
  TGTAGAACGCTCAGTATCAGATCTTTATAAAATGAAGCACTCAGTGCCTCAGAGTTTACCCCAAAGTAAC
  TATTTCACTACATTGTCTAATAGTGTGGTCAATGAACCACCAAGATCATACCCATCCAAAGAAGTTTCAA
  ATATTTACGGTGATAAACAGAGTAATGCCCTTGCAGCGGCAGCAGCTAATCCTCAAACTCTGACTTCATT
  TATAACATCTCTTTCAAAGCCTCCACCTTTGATTAAACACCAACCAGAAAGTGAAGGTTTAGTAGGCAAG
  ATACCAGAACATCTTCCACATCAGATTGCATCTCACTCAGTAACAACCTTCAGAAATGATTGTAGGAGTC
  CTACCCATTTGACAGTTTCTTCTACAAATACACTCCGCAGTATGCCTGCATTACATAGAGCACCAGTATT
  TCACCCACCAATCCATCACAGCCTGGAAAGAAAGGAAGGCAGCTATAGTAGTCTTTCCCCTCCAACTTTA
  ACTCCGGTGATGCCAGTAAATGCTGGTGGTAAAGTTCAAGAATCACAGAAGCCTCCAACTCTAATACCCG
  AACCAAAAGACTCCCAGGCAAATTTTAAGAGTTCTTCAGAACAGAGTTTGACGGAGATGTGGAGACCTAA
  TAATAACCTCAGCAAAGAGAAAACTGAATGGCATGTGGAGAAAAGCAGCGGAAAGTTACAGGCTGCTATG
  GCATCTGTCATTGTGCGTCCATCTTCTAGTACAAAAACTGATAGTATGCCAGCAATGCAGTTAGCTTCTA
  AAGATCGAGTTAGTGAAAGATCTTCAGCTGGGGCACATAAAACAGATTGCCTCAAACTAGCAGAAGCCGG
  AGAAACTGGAAGAATCATTTTGCCAAATGTGAATTCAGACAGTGTTCACACAAAATCTGAAAAAAACTTT
  CAGGCTGTCTCACAGGGCAGTGTTCCCAGTTCAGTCATGTCTGCTGTAAATACGATGTGTAATACCAAAA
  CGGATGTAATCACATCTGCTGCCGATACTACCAGTGTTTCCAGCTGGGGTGGTTCAGAAGTAATTTCCTC
  TTTATCAAATACCATTTTGGCCTCTACATCATCAGAATGTGTATCTTCAAAAAGTGTCAGTCAGCCAGTG
  GCTCAAAAACAAGAATGCAAGGTCAGCACCACAGCACCAGTTACATTAGCCAGTAGTAAGACAGGAAGTG
  TTGTTCAACCCAGTTCTGGGTTCTCAGGCACAACTGATTTTATCCATTTAAAAAAGCACAAGGCAGCATT
  GGCTGCAGCTCAGTATAAAAGTAGTAATGCCAGTGAGACTGAACCTAATGCTATAAAAAATCAGACACTT
  TCAGCCTCCCTTCCTCTGGATAGCACTGTAATCTGTAGTACAATTAACAAAGCAAACTCTGTAGGAAATG
  GGCAAGCTTCCCAGACAAGTCAACCAAACTACCATACTAAACTGAAAAAGGCCTGGCTCACCAGACACTC
  AGAAGAAGATAAAAATACTAATAAAATGGAAAATTCAGGGAATTCTGTATCAGAAATTATTAAGCCATGT
  TCTGTCAACTTAATAGCCTCTACATCTAGTGATATACAAAATAGTGTAGATAGTAAGATCATAGTTGATA
  AATATGTAAAAGATGATAAAGTCAACAGGAGAAAAGCCAAAAGAACTTATGAATCTGGCTCTGAAAGTGG
  AGACTCAGATGAAAGTGAAAGCAAGTCAGAGCAAAGGACTAAAAGACAACCTAAGCCAACTTACAAAAAG
  AAGCAAAATGATTTGCAAAAGAGAAAAGGTGAAATAGAAGAAGATTTGAAACCCAATGGAGTTCTCAGCA
  GGAGTGCCAAAGAAAGAAGTAAACTGAAGTTGCAAAGCAACAGTAATACTGGCATTCCTCGTTCAGTATT
  GAAAGATTGGCGTAAAGTCAAGAAGCTGAAGCAAACTGGGGAATCCTTTTTACAGGATGACTCCTGCTGT
  GAGATAGGGCCTAATTTACAAAAGTGTCGAGAATGTAGACTTATTCGCAGTAAAAAAGGAGAAGAACCAG
  CTCACTCACCAGTATTTTGTAGATTTTACTACTTTAGACGGTTGTCATTTAGTAAAAACGGAGTAGTTAG
  AATAGATGGTTTCTCTTCTCCTGACCAATATGATGATGAAGCTATGAGTTTGTGGACACATGAAAATTTT
  GAAGATGATGAACTAGATATAGAGACTTCTAAATATATCTTGGATATAATAGGTGATAAGTTCTGTCAAT
  TAGTAACATCTGAAAAAACAGCTTTGTCCTGGGTGAAAAAGGATGCCAAAATTGCCTGGAAAAGAGCAGT
  GAGAGGAGTCCGGGAGATGTGTGATGCATGTGAAGCAACATTGTTTAACATTCACTGGGTCTGCCAAAAA
  TGTGGATTTGTGGTCTGCTTAGATTGTTACAAGGCAAAGGAAAGGAAGAGTTCTAGAGATAAAGAACTAT
  ATGCTTGGATGAAGTGTGTGAAGGGACAGCCTCATGATCACAAACATTTAATGCCAACCCAAATTATACC
  TGGTTCTGTTTTGACAGATCTTCTAGATGCCATGCACACTCTTAGGGAAAAATATGGTATTAAATCCCAT
  TGTCATTGTACTAACAAACAGAATTTACAAGTTGGAAATTTTCCTACAATGAATGGTGTATCTCAAGTTT
  TACAGAATGTTCTTAATCACAGTAATAAAATTTCTCTGTGCATGCCTGAGTCTCAGCAGCAAAATACTCC
  TCCGAAGTCTGAGAAAAATGGTGGCAGCAGCCCAGAGAGTGATGTAGGCACAGATAACAAGTTAACTCCT
  CCAGAATCCCAGTCACCACTGCACTGGTTAGCAGATCTTGCAGAGCAAAAAGCCAGAGAGGAAAAAAAAG
  AAAACAAAGAACTTACCCTTGAAAACCAAATTAAAGAAGAAAGAGAACAAGACAACTCTGAATCTCCAAA
  TGGCAGAACATCACCTCTTGTGTCCCAGAATAATGAACAAGGCTCAACCTTACGGGATTTGCTGACTACA
  ACAGCTGGAAAGCTACGTGTGGGGTCTACAGATGCTGGCATTGCCTTTGCCCCAGTATATTCAATGGGAG
  CCCCAAGTAGCAAAAGTGGACGGACTATGCCTAACATTCTTGATGACATAATTGCTTCAGTTGTTGAAAA
  CAAAATTCCACCAAGTAAAACCTCCAAGATAAATGTAAAACCAGAGCTTAAAGAAGAGCCTGAAGAAAGC
  ATAATATCTGCAGTGGATGAAAATAATAAATTATACAGTGATATACCACATTCTTGGATCTGTGAGAAGC
  ATATTTTATGGCTTAAGGATTATAAGAATAGCAGTAATTGGAAGCTTTTCAAAGAATGTTGGAAACAAGG
  ACAGCCTGCAGTGGTTTCTGGTGTGCATAAGAAAATGAACATTAGCCTATGGAAGGCGGAATCAATTAGT
  CTTGATTTTGGAGACCACCAAGCTGATCTCCTGAACTGCAAAGATAGCATCATTTCAAATGCCAATGTTA
  AGGAATTCTGGGATGGTTTTGAAGAAGTTTCAAAACGGCAGAAAAACAAGAGTGGAGAAACAGTTGTTTT
  AAAATTGAAAGACTGGCCTTCAGGAGAAGACTTCAAGACTATGATGCCAGCAAGATACGAAGATCTTTTA
  AAAAGTCTGCCATTGCCAGAATATTGTAATCCAGAAGGAAAATTCAATTTGGCCTCTCATTTGCCAGGAT
  TTTTTGTACGTCCTGATCTAGGACCCAGGTTGTGCAGTGCCTATGGTGTAGTTGCTGCTAAAGATCATGA
  TATAGGAACAACAAATCTCCATATTGAAGTTTCTGATGTTGTAAATATACTAGTTTATGTTGGCATAGCA
  AAAGGAAATGGCATTCTCTCAAAAGCAGGAATTCTCAAGAAATTTGAGGAAGAAGATTTGGATGACATTT
  TAAGGAAAAGATTGAAGGACTCAAGTGAAATACCTGGTGCTCTGTGGCATATTTATGCTGGGAAAGATGT
  TGACAAGATAAGGGAATTTCTTCAAAAGATTTCAAAAGAACAAGGCCTTGAAGTTCTACCAGAACATGAT
  CCAATACGTGACCAAAGTTGGTATGTGAACAAAAAGCTCCGTCAAAGGCTGCTTGAAGAATATGGAGTCA
  GAACCTGTACTCTTATTCAGTTCCTTGGTGATGCTATTGTTTTGCCAGCGGGAGCACTTCATCAGGTTCA
  GAATTTTCACAGCTGTATTCAGGTAACTGAAGATTTTGTGTCTCCAGAACATCTTGTAGAGTCATTTCAT
  TTAACACAGGAACTGAGACTTTTGAAGGAAGAAATCAATTATGATGATAAACTACAGGTTAAAAATATTT
  TGTATCATGCAGTCAAAGAAATGGTGAGAGCCTTGAAGATACACGAGGATGAAGTAGAGGATATGGAAGA
  AAATTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001282948
• ORF Size: 7077 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001282948.1, NP_001269877.1
• RefSeq Size: 8675
• RefSeq ORF: 7077
• Locus ID: 221037
• Protein Families: Druggable Genome
• Gene Summary: The protein encoded by this gene interacts with thyroid hormone receptors and contains a jumonji domain. It is a candidate histone demethylase and is thought to be a coactivator for key transcription factors. It plays a role in the DNA-damage response pathway by demethylating the mediator of DNA damage checkpoint 1 (MDC1) protein, and is required for the survival of acute myeloid leukemia. Mutations in this gene are associated with Rett syndrome and intellectual disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
  Transcript Variant: This variant (3) contains alternate 5' exon structure, and it thus differs in the 5' UTR and initiates translation from a downstream in-frame start codon, compared to variant 1. The encoded isoform (c, also known as s-JMJD1C) is shorter at the N-terminus, compared to isoform a. Both variants 3 and 4 encode isoform c.