EDD (UBR5) (NM_001282873) Human Untagged Clone

CAT#: SC338150

UBR5 (untagged) - Human ubiquitin protein ligase E3 component n-recognin 5 (UBR5), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: UBR5
• Synonyms: DD5; EDD; EDD1; HYD
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001282873, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGACGTCCATCCATTTCGTGGTTCACCCGCTGCCGGGCACCGAGGACCAGCTCAATGACAGGTTACGAG
  AAGTTTCTGAGAAGCTGAACAAATATAATTTAAACAGCCACCCCCCTTTGAATGTATTGGAACAGGCTAC
  TATTAAACAGTGTGTGGTGGGACCAAATCATGCTGCCTTTCTTCTTGAGGATGGTAGAGTTTGCAGGATT
  GGTTTTTCAGTACAGCCAGACAGATTGGAATTGGGTAAACCTGATAATAATGATGGGTCAAAGTTGAACA
  GCAACTCGGGGGCAGGGAGGACGTCAAGGCCTGGTAGGACAAGCGACTCTCCATGGTTTCTCTCAGGTTC
  TGAGACTCTAGGCAGGCTGGCAGGCAACACCTTAGGAAGCCGCTGGAGTTCTGGAGTGGGTGGAAGTGGT
  GGAGGATCCTCTGGTAGGTCATCAGCTGGAGCTCGAGATTCCCGCCGGCAGACTCGAGTTATTCGGACAG
  GACGGGATCGAGGGTCTGGGCTTTTGGGCAGTCAGCCCCAGCCAGTTATTCCAGCATCTGTCATTCCAGA
  GGAGCTGATTTCACAGGCCCAAGTTGTTTTACAAGGCAAATCCAGAAGTGTCATTATTCGAGAACTTCAG
  AGAACAAATCTTGATGTGAACCTTGCTGTAAATAATTTACTTAGCCGGGATGATGAAGATGGAGATGATG
  GGGATGATACAGCCAGCGAATCTTATTTGCCTGGAGAGGATCTTATGTCTCTCCTTGATGCCGACATTCA
  TTCTGCCCACCCAAGTGTCATTATTGATGCAGATGCCATGTTTTCTGAAGACATTAGCTATTTTGGTTAC
  CCTTCTTTTCGTCGTTCATCACTTTCCAGGCTAGGCTCATCTCGAGTTCTCCTTCTTCCCTTAGAGAGAG
  ACTCTGAGCTGTTGCGTGAACGTGAATCCGTTTTACGTTTACGTGAACGAAGGTGGCTTGATGGAGCCTC
  ATTTGATAATGAAAGGGGTTCTACCAGCAAGGAAGGAGAGCCAAACTTGGATAAGAAGAATACACCTGTT
  CAAAGTCCAGTATCTCTAGGAGAAGATTTGCAGTGGTGGCCTGATAAGGATGGAACAAAATTCATCTGTA
  TTGGGGCTCTGTATTCTGAACTTCTGGCTGTCAGCAGTAAAGGAGAACTTTATCAGTGGAAATGGAGTGA
  ATCTGAGCCTTACAGAAATGCCCAGAATCCTTCATTACATCATCCACGAGCAACATTTTTGGGGTTAACC
  AATGAAAAGATAGTCCTCCTGTCTGCAAATAGCATAAGAGCAACTGTAGCTACAGAAAATAACAAGGTTG
  CTACATGGGTGGATGAAACTTTAAGTTCTGTGGCTTCTAAATTAGAGCACACTGCTCAGACTTACTCTGA
  ACTTCAAGGAGAGCGGATAGTTTCTTTACATTGCTGTGCCCTTTACACCTGCGCTCAGCTGGAAAACAGT
  TTATATTGGTGGGGTGTAGTTCCTTTTAGTCAAAGGAAGAAAATGTTAGAGAAAGCTAGAGCAAAAAATA
  AAAAGCCTAAATCCAGTGCTGGTATTTCTTCAATGCCGAACATCACTGTTGGTACCCAGGTATGCTTGAG
  AAATAATCCTCTTTATCATGCTGGAGCAGTTGCATTTTCAATTAGTGCTGGGATTCCTAAAGTTGGTGTC
  TTAATGGAGTCAGTTTGGAATATGAATGACAGCTGTAGATTTCAACTTAGATCTCCTGAAAGCTTGAAAA
  ACATGGAAAAAGCTAGCAAAACTACTGAAGCTAAGCCTGAAAGTAAGCAGGAGCCAGTGAAAACAGAAAT
  GGGTCCTCCACCATCTCCAGCATCCACGTGTAGTGATGCATCCTCAATTGCCAGCAGTGCATCAATGCCA
  TACAAACGACGACGGTCAACCCCTGCACCAAAAGAAGAGGAAAAGGTGAATGAAGAGCAGTGGTCTCTTC
  GGGAAGTGGTTTTTGTGGAAGATGTCAAGAATGTTCCTGTTGGCAAGGTGCTAAAAGTAGATGGTGCCTA
  TGTTGCTGTAAAATTTCCAGGAACCTCCAGTAATACTAACTGTCAGAACAGCTCTGGTCCAGATGCTGAC
  CCTTCTTCTCTCCTGCAGGATTGTAGGTTACTTAGAATTGATGAATTGCAGGTTGTCAAAACTGGTGGAA
  CACCGAAGGTTCCCGACTGTTTCCAAAGGACTCCTAAAAAGCTTTGTATACCTGAAAAAACAGAAATATT
  AGCAGTGAATGTAGATTCCAAAGGTGTTCATGCTGTTCTGAAGACTGGAAATTGGGTACGATACTGTATC
  TTTGATCTTGCTACAGGAAAAGCAGAACAGGAAAATAATTTTCCTACAAGCAGCATTGCTTTCCTTGGTC
  AGAATGAGAGGAATGTAGCCATTTTCACTGCTGGACAGGAATCTCCCATTATTCTTCGAGATGGAAATGG
  TACCATCTACCCAATGGCCAAAGATTGCATGGGAGGAATAAGGGATCCCGATTGGCTGGATCTTCCACCT
  ATTAGTAGTCTTGGAATGGGTGTGCATTCTTTAATAAATCTTCCTGCCAATTCAACAATCAAAAAGAAAG
  CTGCTGTTATCATCATGGCTGTAGAGAAACAAACCTTAATGCAACACATTCTGCGCTGTGACTATGAGGC
  CTGTCGACAATATCTAATGAATCTTGAGCAAGCGGTTGTTTTAGAGCAGAATCTACAGATGCTGCAGACA
  TTCATCAGCCACAGATGTGATGGAAATCGAAATATTTTGCATGCTTGTGTATCAGTTTGCTTTCCAACCA
  GCAATAAAGAAACTAAAGAAGAAGAGGAAGCGGAGCGTTCTGAAAGAAATACATTTGCAGAAAGGCTTTC
  TGCTGTTGAGGCCATTGCAAATGCAATATCAGTTGTTTCAAGTAATGGCCCAGGTAATCGGGCTGGATCA
  TCAAGTAGCCGAAGTTTGAGATTACGGGAAATGATGAGACGTTCGTTGAGAGCAGCTGGTTTGGGTAGAC
  ATGAAGCTGGAGCTTCATCCAGTGACCACCAGGATCCAGTTTCACCCCCCATAGCTCCCCCTAGTTGGGT
  TCCTGACCCTCCTGCGATGGATCCTGATGGTGACATTGATTTTATCCTGGCCCCCGCTGTGGGATCTCTT
  ACCACAGCAGCAACCGGTACTGGTCAAGGACCAAGCACCTCCACTATTCCAGGTCCTTCCACAGAGCCAT
  CTGTAGTAGAATCCAAGGATCGAAAGGCGAATGCTCATTTTATATTGAAATTGTTATGTGACAGTGTGGT
  TCTCCAGCCCTATCTACGAGAACTTCTTTCTGCCAAGGATGCAAGAGGGATGACCCCATTTATGTCAGCT
  GTAAGTGGCCGAGCTTATCCTGCTGCAATTACCATCTTAGAAACTGCTCAGAAAATTGCAAAAGCTGAAA
  TATCCTCAAGTGAAAAAGAGGAAGATGTATTCATGGGAATGGTTTGCCCATCAGGTACCAACCCTGATGA
  CTCTCCTTTATATGTTTTATGTTGTAATGACACTTGCAGTTTTACATGGACTGGAGCAGAGCACATTAAC
  CAGGATATTTTTGAGTGTCGAACTTGTGGCTTGCTGGAGTCACTGTGTTGTTGTACGGAATGTGCAAGGG
  TTTGTCATAAAGGTCATGATTGCAAACTCAAACGGACATCACCAACAGCCTACTGTGATTGTTGGGAGAA
  ATGTAAATGTAAAACTCTTATTGCTGGACAGAAATCTGCTCGTCTTGATCTACTTTATCGCCTGCTCACT
  GCTACTAATCTGGTTACTCTGCCAAACAGCAGGGGAGAGCACCTCTTACTATTCTTAGTACAGACAGTCG
  CAAGGCAGACGGTGGAGCATTGTCAATACAGGCCACCTCGAATCAGGGAAGATCGTAACCGAAAAACAGC
  CAGTCCTGAAGATTCAGATATGCCAGATCATGATTTAGAGCCTCCAAGATTTGCCCAGCTTGCATTGGAG
  CGTGTTCTACAGGACTGGAATGCCTTGAAATCTATGATTATGTTTGGGTCGCAGGAGAATAAAGACCCTC
  TTAGTGCCAGCAGTAGAATAGGCCATCTTTTGCCAGAAGAGCAAGTATACCTCAATCAGCAAAGTGGCAC
  AATTCGGCTGGACTGTTTCACTCATTGCCTTATAGTTAAGTGTACAGCAGATATTTTGCTTTTAGATACT
  CTACTAGGTACACTAGTGAAAGAACTCCAAAACAAATATACACCTGGACGTAGAGAAGAAGCTATTGCTG
  TGACAATGAGGTTTCTACGTTCAGTGGCAAGAGTTTTTGTTATTCTGAGTGTGGAAATGGCTTCATCCAA
  AAAGAAAAACAACTTTATTCCACAGCCAATTGGAAAATGCAAGCGTGTATTCCAAGCATTGCTACCTTAC
  GCTGTGGAAGAATTGTGCAACGTAGCAGAGTCACTGATTGTTCCTGTCAGAATGGGGATTGCTCGTCCAA
  CTGCACCATTTACCCTGGCTAGTACTAGCATAGATGCCATGCAGGGCAGTGAAGAATTATTTTCAGTGGA
  ACCACTACCACCACGACCATCATCTGATCAGTCTAGCAGCTCCAGTCAGTCTCAGTCATCCTACATCATC
  AGGAATCCACAGCAGAGGCGCATCAGCCAGTCACAGCCCGTTCGGGGCAGAGATGAAGAACAGGATGATA
  TTGTTTCAGCAGATGTGGAAGAGGTTGAGGTGGTGGAGGGTGTGGCTGGAGAAGAGGATCATCATGATGA
  ACAGGAAGAACACGGGGAAGAAAATGCTGAGGCAGAGGGACAACATGATGAGCATGATGAAGACGGGAGT
  GATATGGAGCTGGACTTGTTAGCAGCAGCTGAAACAGAAAGTGATAGTGAAAGTAACCACAGCAACCAAG
  ATAATGCTAGTGGGCGCAGAAGCGTTGTCACTGCAGCAACTGCTGGTTCAGAAGCAGGAGCAAGCAGTGT
  TCCTGCCTTCTTTTCTGAAGATGATTCTCAATCGAATGACTCAAGTGATTCTGATAGCAGTAGTAGTCAG
  AGTGACGACATAGAACAGGAGACCTTTATGCTTGATGAGCCATTAGAAAGAACCACAAATAGCTCCCATG
  CCAATGGTGCTGCCCAAGCTCCCCGTTCAATGCAGTGGGCTGTCCGCAACACCCAGCATCAGCGAGCAGC
  CAGTACAGCCCCTTCCAGTACATCTACACCAGCAGCAAGTTCAGCGGGTTTGATTTATATTGATCCTTCA
  AACTTACGCCGGAGTGGTACCATCAGTACAAGTGCTGCAGCTGCAGCAGCTGCTTTGGAAGCTAGCAACG
  CCAGCAGTTACCTAACATCTGCAAGCAGTTTAGCCAGGGCTTACAGCATTGTCATTAGACAAATCTCGGA
  CTTGATGGGCCTTATTCCTAAGTATAATCACCTAGTATACTCTCAGATTCCAGCAGCTGTGAAATTGACT
  TACCAAGATGCAGTAAACTTACAGAACTATGTAGAAGAAAAGCTTATTCCCACTTGGAACTGGATGGTCA
  GTATTATGGATTCTACTGAAGCTCAATTACGTTATGGTTCTGCATTAGCATCTGCTGGTGATCCTGGACA
  TCCAAATCATCCTCTTCACGCTTCTCAGAATTCAGCGAGAAGAGAGAGGATGACTGCGCGAGAAGAAGCT
  AGCTTACGAACACTTGAAGGCAGACGACGTGCCACCTTGCTTAGCGCCCGTCAAGGAATGATGTCTGCAC
  GAGGAGACTTCCTAAATTATGCTCTGTCTCTAATGCGGTCTCATAATGATGAGCATTCTGATGTTCTTCC
  AGTTTTGGATGTTTGCTCATTGAAGCATGTGGCATATGTTTTTCAAGCACTTATATACTGGATTAAGGCA
  ATGAATCAGCAGACAACATTGGATACACCTCAACTAGAACGCAAAAGGACGCGAGAACTCTTGGAACTGG
  GTATTGATAATGAAGATTCAGAACATGAAAATGATGATGACACCAATCAAAGTGCTACTTTGAATGATAA
  GGATGATGACTCTCTTCCTGCAGAAACTGGCCAAAACCATCCATTTTTCCGACGTTCAGACTCCATGACA
  TTCCTTGGGTGTATACCCCCAAATCCATTTGAAGTGCCTCTGGCTGAAGCCATCCCCTTGGCTGATCAGC
  CACATCTGTTGCAGCCAAATGCTAGAAAGGAGGATCTTTTTGGCCGTCCAAGTCAGGGTCTTTATTCTTC
  ATCTGCCAGTAGTGGGAAATGTTTAATGGAGGTTACAGTGGATAGAAACTGCCTAGAGGTTCTTCCAACA
  AAAATGTCTTATGCTGCCAATCTGAAAAATGTAATGAACATGCAAAACCGGCAAAAAAAAGAAGGGGAAG
  AACAGCCCGTGCTGCCAGAAGAAACTGAGAGTTCAAAACCAGGGCCATCTGCTCATGATCTTGCTGCACA
  ATTAAAAAGTAGCTTACTAGCAGAAATAGGACTTACTGAAAGTGAAGGGCCACCTCTCACATCTTTCAGG
  CCACAGTGTAGCTTTATGGGAATGGTTATTTCCCATGATATGCTGCTAGGACGTTGGCGCCTTTCTTTAG
  AACTGTTCGGCAGGGTATTCATGGAAGATGTTGGAGCAGAACCTGGATCAATCCTAACTGAATTGGGTGG
  TTTTGAGGTAAAAGAATCAAAATTCCGCAGAGAAATGGAAAAACTGAGAAACCAGCAGTCAAGAGATTTG
  TCACTAGAGGTTGATCGGGATCGAGATCTTCTCATTCAGCAGACTATGAGGCAGCTTAACAATCACTTTG
  GTCGAAGATGTGCTACTACACCAATGGCTGTACACAGAGTAAAAGTCACATTTAAGGATGAGCCAGGAGA
  GGGCAGTGGTGTAGCACGAAGTTTTTATACAGCCATTGCACAAGCATTTTTATCAAATGAAAAATTGCCA
  AATCTAGAGTGTATCCAAAATGCCAACAAAGGCACCCACACAAGTTTAATGCAGAGATTAAGGAACCGAG
  GAGAGAGAGACCGGGAAAGGGAGAGAGAAAGGGAAATGAGGAGGAGTAGTGGTTTGCGAGCAGGTTCTCG
  GAGGGACCGGGATAGAGACTTTAGAAGACAGCTTTCCATCGACACTAGGCCCTTTAGACCAGCCTCTGAA
  GGGAATCCTAGCGATGATCCTGAGCCTTTGCCAGCACATCGGCAGGCACTTGGAGAGAGGCTTTATCCTC
  GTGTACAAGCAATGCAACCAGCATTTGCAAGTAAAATCACTGGCATGTTGTTGGAATTATCCCCAGCTCA
  GCTGCTTCTCCTTCTAGCAAGTGAGGATTCTCTGAGAGCAAGAGTGGATGAGGCCATGGAACTCATTATT
  GCACATGGACGGGAAAATGGAGCTGATAGTATCCTGGATCTTGGATTAGTAGACTCCTCAGAAAAGGTAC
  AGGAAAACCGAAAGCGCCATGGCTCTAGTCGAAGTGTAGTAGATATGGATTTAGATGATACAGATGATGG
  TGATGACAATGCCCCTTTGTTTTACCAACCTGGGAAAAGAGGATTTTATACTCCAAGGCCTGGCAAGAAC
  ACAGAAGCAAGGTTGAATTGTTTCAGAAACATTGGCAGGATTCTTGGACTATGTCTGTTACAGAATGAAC
  TATGTCCTATCACATTGAATAGACATGTAATTAAAGTATTGCTTGGTAGAAAAGTCAATTGGCATGATTT
  TGCTTTTTTTGATCCTGTAATGTATGAGAGTTTGCGGCAACTAATCCTCGCGTCTCAGAGTTCAGATGCT
  GATGCTGTTTTCTCAGCAATGGATTTGGCATTTGCAATTGACCTGTGTAAAGAAGAAGGTGGAGGACAGG
  TTGAACTCATTCCTAATGGTGTAAATATACCAGTCACTCCACAGAATGTATATGAGTATGTGCGGAAATA
  CGCAGAACACAGAATGTTGGTAGTTGCAGAACAGCCCTTACATGCAATGAGGAAAGGTCTACTAGATGTG
  CTTCCAAAAAATTCATTAGAAGATTTAACGGCAGAAGATTTTAGGCTTTTGGTAAATGGCTGCGGTGAAG
  TCAATGTGCAAATGCTGATCAGTTTTACCTCTTTCAATGATGAATCAGGAGAAAATGCTGAGAAGCTTCT
  GCAGTTCAAGCGTTGGTTCTGGTCAATAGTAGAGAAGATGAGCATGACAGAACGACAAGATCTTGTTTAC
  TTTTGGACATCAAGCCCATCACTGCCAGCCAGTGAAGAAGGATTCCAGCCTATGCCCTCAATCACAATAA
  GACCACCAGATGACCAACATCTTCCTACTGCAAATACTTGCATTTCTCGACTTTACGTCCCACTCTATTC
  CTCTAAACAGATTCTCAAACAGAAATTGTTACTCGCCATTAAGACCAAGAATTTTGGTTTTGTGTAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001282873
• ORF Size: 8397 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001282873.1, NP_001269802.1
• RefSeq Size: 10897
• RefSeq ORF: 8397
• Locus ID: 51366
• Protein Families: Druggable Genome
• Protein Pathways: Ubiquitin mediated proteolysis
• Gene Summary: This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) uses an alternate in-frame splice site compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.