Fmo3 (NM_008030) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR220435L3V

Lenti ORF particles, Fmo3 (Myc-DDK-tagged) - Mouse flavin containing monooxygenase 3 (Fmo3), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Fmo3
• Synonyms: AW111792
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_008030
• ORF Size: 1602 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR220435).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_008030.1, NP_032056.1
• RefSeq Size: 2020 bp
• RefSeq ORF: 1605 bp
• Locus ID: 14262
• UniProt ID: P97501
• Cytogenetics: 1 70.34 cM
• Gene Summary: Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds. Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite. TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thrombus formation.[UniProtKB/Swiss-Prot Function]