Angiopoietin like 7 (ANGPTL7) (NM_021146) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC200321L1V

Lenti ORF particles, ANGPTL7 (Myc-DDK tagged) - Human angiopoietin-like 7 (ANGPTL7), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: Angiopoietin like 7
• Synonyms: AngX; CDT6; dJ647M16.1
• Mammalian Cell Selection: None
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_021146
• ORF Size: 1038 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC200321).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_021146.2
• RefSeq Size: 2307 bp
• RefSeq ORF: 1041 bp
• Locus ID: 10218
• UniProt ID: O43827
• Cytogenetics: 1p36.22
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• MW: 40 kDa
• Gene Summary: Has a role in the formation and organization of the extracellular matrix. In the eye, it functions as a mediator of dexamethasone-induced matrix deposition in the trabecular meshwork, the tissue responsible for the outflow of the ocular aqueous humor and for the maintenance of intraocular pressure (PubMed:21199193). Is a negative regulator of angiogenesis in the cornea, and plays a major role in maintaining corneal avascularity and transparency (PubMed:25622036).[UniProtKB/Swiss-Prot Function]