ICAM2 (NM_000873) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC200459L2V
- LentiORF®
Lenti ORF particles, ICAM2 (mGFP-tagged) - Human intercellular adhesion molecule 2 (ICAM2), transcript variant 5, 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | ICAM2 |
Synonyms | CD102 |
Vector | pLenti-C-mGFP |
ACCN | NM_000873 |
ORF Size | 825 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC200459).
|
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_000873.2, NP_000864.1 |
RefSeq Size | 1229 bp |
RefSeq ORF | 828 bp |
Locus ID | 3384 |
Cytogenetics | 17q23.3 |
Domains | ICAM_N |
Protein Families | ES Cell Differentiation/IPS, Transmembrane |
Protein Pathways | Cell adhesion molecules (CAMs), Natural killer cell mediated cytotoxicity |
MW | 30.7 kDa |
Gene Summary | 'The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]' |
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