POLR2C (NM_032940) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC201317L3V

Lenti ORF particles, POLR2C (Myc-DDK tagged) - Human polymerase (RNA) II (DNA directed) polypeptide C, 33kDa (POLR2C), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: POLR2C
• Synonyms: hRPB33; hsRPB3; RPB3; RPB31
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_032940
• ORF Size: 825 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC201317).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_032940.2, NP_116558.1
• RefSeq Size: 1822 bp
• RefSeq ORF: 828 bp
• Locus ID: 5432
• Cytogenetics: 16q21
• Domains: RNA_pol_A_bac
• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Huntington's disease, Metabolic pathways, Purine metabolism, Pyrimidine metabolism, RNA polymerase
• MW: 31.4 kDa
• Gene Summary: 'This gene encodes the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with another polymerase subunit, POLR2J. These two subunits form a core subassembly unit of the polymerase. A pseudogene has been identified on chromosome 21. [provided by RefSeq, Jul 2008]'