AP2M1 (NM_001025205) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC201377L3V

Lenti ORF particles, AP2M1 (Myc-DDK tagged) - Human adaptor-related protein complex 2, mu 1 subunit (AP2M1), transcript variant 2, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: AP2M1
• Synonyms: AP50; CLAPM1; MRD60; mu2
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_001025205
• ORF Size: 1305 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC201377).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001025205.1, NP_001020376.1
• RefSeq Size: 1952 bp
• RefSeq ORF: 1302 bp
• Locus ID: 1173
• Cytogenetics: 3q27.1
• Protein Families: Druggable Genome
• Protein Pathways: Endocytosis, Huntington's disease
• MW: 49.2 kDa
• Gene Summary: 'This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015]'