ORC2 (NM_006190) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC201599L3V
- LentiORF®
Lenti ORF particles, ORC2 (Myc-DDK tagged) - Human origin recognition complex, subunit 2 (ORC2), transcript variant 1, 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | ORC2 |
Synonyms | ORC2L |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_006190 |
ORF Size | 1731 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC201599).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_006190.3, NP_006181.1 |
RefSeq Size | 3140 bp |
RefSeq ORF | 1734 bp |
Locus ID | 4999 |
Cytogenetics | 2q33.1 |
Domains | ORC2 |
Protein Families | Stem cell - Pluripotency, Transcription Factors |
Protein Pathways | Cell cycle |
MW | 66 kDa |
Gene Summary | 'The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3, -4, and -5. It also interacts with CDC45 and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication. Alternatively spliced transcript variants have been found, one of which is a nonsense-mediated mRNA decay candidate. [provided by RefSeq, Oct 2010]' |
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