PLOD1 (NM_000302) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC201969L1V

  • LentiORF®

Lenti ORF particles, PLOD1 (Myc-DDK tagged) - Human procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1 (PLOD1), 200ul, >10^7 TU/mL

Biosafety Sheet

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USD 1,010.00

3 Weeks*

Size
    • 200 ul

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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Symbol PLOD1
Synonyms EDS6; EDSKCL1; LH; LH1; LLH; PLOD
Vector pLenti-C-Myc-DDK
ACCN NM_000302
ORF Size 2181 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC201969).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_000302.2, NP_000293.2
RefSeq Size 3047 bp
RefSeq ORF 2184 bp
Locus ID 5351
Cytogenetics 1p36.22
Domains 2OG-FeII_Oxy, P4Hc
Protein Families Druggable Genome
Protein Pathways Lysine degradation
MW 83.6 kDa
Gene Summary 'Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]'

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.