EAP30 (SNF8) (NM_007241) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC202137L4V

Lenti ORF particles, SNF8 (mGFP-tagged) - Human SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) (SNF8), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: SNF8
• Synonyms: Dot3; EAP30; VPS22
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_007241
• ORF Size: 774 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC202137).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_007241.2, NP_009172.2
• RefSeq Size: 1226
• RefSeq ORF: 777
• Locus ID: 11267
• Domains: EAP30
• Protein Families: Transcription Factors
• Protein Pathways: Endocytosis
• MW: 28.9 kDa
• Gene Summary: The protein encoded by this gene is a component of the endosomal sorting complex required for transport II (ESCRT-II), which regulates the movement of ubiquitinylated transmembrane proteins to the lysosome for degradation. This complex also interacts with the RNA polymerase II elongation factor (ELL) to overcome the repressive effects of ELL on RNA polymerase II activity. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]