AICDA (NM_020661) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC202949L4V

Lenti ORF particles, AICDA (mGFP-tagged) - Human activation-induced cytidine deaminase (AICDA), 200ul, >10^7 TU/mL

Product Images

RC202949L4 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC202949L4V particle to overexpress human AICDA-mGFP fusion protein.

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: AICDA
• Synonyms: AID; ARP2; CDA2; HEL-S-284; HIGM2
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_020661
• ORF Size: 594 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC202949).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_020661.1, NP_065712.1
• RefSeq Size: 2794 bp
• RefSeq ORF: 597 bp
• Locus ID: 57379
• UniProt ID: Q9GZX7, Q546Y9, Q7Z599
• Cytogenetics: 12p13.31
• Protein Families: Druggable Genome
• Protein Pathways: Primary immunodeficiency
• MW: 24 kDa
• Gene Summary: This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2). [provided by RefSeq, Feb 2009]