SDHD (NM_003002) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC203269L2V
- LentiORF®
Lenti ORF particles, SDHD (mGFP-tagged) - Human succinate dehydrogenase complex, subunit D, integral membrane protein (SDHD), nuclear gene encoding mitochondrial protein, 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | SDHD |
Synonyms | CBT1; CII-4; CWS3; cybS; PGL; PGL1; QPs3; SDH4 |
Vector | pLenti-C-mGFP |
ACCN | NM_003002 |
ORF Size | 477 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC203269).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_003002.1, NP_002993.1 |
RefSeq Size | 1395 bp |
RefSeq ORF | 480 bp |
Locus ID | 6392 |
Cytogenetics | 11q23.1 |
Protein Pathways | Alzheimer's disease, Citrate cycle (TCA cycle), Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease |
MW | 17 kDa |
Gene Summary | 'This gene encodes a member of complex II of the respiratory chain, which is responsible for the oxidation of succinate. The encoded protein is one of two integral membrane proteins anchoring the complex to the matrix side of the mitochondrial inner membrane. Mutations in this gene are associated with the formation of tumors, including hereditary paraganglioma. Transmission of disease occurs almost exclusively through the paternal allele, suggesting that this locus may be maternally imprinted. There are pseudogenes for this gene on chromosomes 1, 2, 3, 7, and 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013]' |
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