RHOH (NM_004310) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC204324L4V

Lenti ORF particles, RHOH (mGFP-tagged) - Human ras homolog gene family, member H (RHOH), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: RHOH
• Synonyms: ARHH; TTF
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_004310
• ORF Size: 573 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC204324).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_004310.2, NP_004301.1
• RefSeq Size: 2102 bp
• RefSeq ORF: 576 bp
• Locus ID: 399
• Cytogenetics: 4p14
• Domains: ras, RAS, RHO, RAB
• Protein Families: Transcription Factors
• Protein Pathways: Leukocyte transendothelial migration
• MW: 21.3 kDa
• Gene Summary: 'The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2013]'