PTS (NM_000317) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC205199L1V

Lenti ORF particles, PTS (Myc-DDK tagged) - Human 6-pyruvoyltetrahydropterin synthase (PTS), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: PTS
• Synonyms: PTPS
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_000317
• ORF Size: 435 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC205199).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_000317.1, NP_000308.1
• RefSeq Size: 948 bp
• RefSeq ORF: 438 bp
• Locus ID: 5805
• Cytogenetics: 11q23.1
• Domains: PTPS
• Protein Families: Druggable Genome
• Protein Pathways: Folate biosynthesis, Metabolic pathways
• MW: 16.4 kDa
• Gene Summary: 'The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia. [provided by RefSeq, Oct 2008]'