SART2 (DSE) (NM_013352) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC206020L4V

  • LentiORF®

Lenti ORF particles, DSE (mGFP-tagged) - Human dermatan sulfate epimerase (DSE), transcript variant 1, 200ul, >10^7 TU/mL


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USD 820.00

6 Weeks*

Size
    • 200 ul

Product Images

Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Symbol DSE
Synonyms DS-epi1; DSEP; DSEPI; EDSMC2; SART-2; SART2
Mammalian Cell Selection Puromycin
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_013352
ORF Size 2874 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC206020).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_013352.2, NP_037484.1
RefSeq Size 4077
RefSeq ORF 2877
Locus ID 29940
Protein Families Transmembrane
Protein Pathways Chondroitin sulfate biosynthesis
MW 109.8 kDa
Gene Summary The protein encoded by this gene is a tumor-rejection antigen. It is localized to the endoplasmic reticulum and functions to convert D-glucuronic acid to L-iduronic acid during the biosynthesis of dermatan sulfate. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. Mutations in this gene cause inmusculocontractural Ehlers-Danlos syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 9, and a paralogous gene exists on chromosome 18. [provided by RefSeq, Apr 2016]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.