CD177 (NM_020406) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC206463L1V

Lenti ORF particles, CD177 (Myc-DDK tagged) - Human CD177 molecule (CD177), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: CD177
• Synonyms: HNA-2a; HNA2A; NB1; NB1 GP; PRV-1; PRV1
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_020406
• ORF Size: 1311 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC206463).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_020406.2, NP_065139.1, NP_065139.2
• RefSeq Size: 2238
• RefSeq ORF: 1314
• Locus ID: 57126
• MW: 46.4 kDa
• Gene Summary: This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified. [provided by RefSeq, Apr 2014]