FECH (NM_000140) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC208058L1V

Lenti ORF particles, FECH (Myc-DDK tagged) - Human ferrochelatase (FECH), nuclear gene encoding mitochondrial protein, transcript variant 2, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: FECH
• Synonyms: EPP; EPP1; FCE
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_000140
• ORF Size: 1269 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC208058).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_000140.2, NP_000131.2
• RefSeq Size: 7277 bp
• RefSeq ORF: 1272 bp
• Locus ID: 2235
• Cytogenetics: 18q21.31
• Domains: Ferrochelatase
• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Porphyrin and chlorophyll metabolism
• MW: 47.9 kDa
• Gene Summary: 'The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome 3.[provided by RefSeq, May 2010]'