SMC3 (NM_005445) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC208401L4V

Lenti ORF particles, SMC3 (mGFP-tagged)-Human structural maintenance of chromosomes 3 (SMC3), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: SMC3
• Synonyms: BAM; BMH; CDLS3; CSPG6; HCAP; SMC3L1
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_005445
• ORF Size: 3651 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC208401).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_005445.3, NP_005436.1
• RefSeq Size: 4131
• RefSeq ORF: 3654
• Locus ID: 9126
• Domains: SMC_N, SMC_C
• Protein Families: Druggable Genome
• Protein Pathways: Cell cycle, Oocyte meiosis
• MW: 142 kDa
• Gene Summary: This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein. [provided by RefSeq, Jul 2008]