LIS1 (PAFAH1B1) (NM_000430) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC209055L2V
- LentiORF®
Lenti ORF particles, PAFAH1B1 (mGFP-tagged) - Human platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) (PAFAH1B1), 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | PAFAH1B1 |
Synonyms | LIS1; LIS2; MDCR; MDS; NudF; PAFAH |
Vector | pLenti-C-mGFP |
ACCN | NM_000430 |
ORF Size | 1230 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC209055).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_000430.2, NP_000421.1 |
RefSeq Size | 5581 bp |
RefSeq ORF | 1233 bp |
Locus ID | 5048 |
Cytogenetics | 17p13.3 |
Domains | WD40, LisH |
Protein Pathways | Ether lipid metabolism, Metabolic pathways |
MW | 46.5 kDa |
Gene Summary | 'This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. This gene encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum. [provided by RefSeq, Apr 2009]' |
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