IGFBP3 (NM_000598) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC209150L2V
- LentiORF®
Lenti ORF particles, IGFBP3 (mGFP-tagged)-Human insulin-like growth factor binding protein 3 (IGFBP3), transcript variant 2, 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | IGFBP3 |
Synonyms | BP-53; IBP3 |
Vector | pLenti-C-mGFP |
ACCN | NM_000598 |
ORF Size | 873 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC209150).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_000598.4, NP_000589.2 |
RefSeq Size | 2620 bp |
RefSeq ORF | 876 bp |
Locus ID | 3486 |
Cytogenetics | 7p12.3 |
Domains | thyroglobulin_1, IB |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | p53 signaling pathway |
MW | 31.67 kDa |
Gene Summary | 'This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]' |
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