HTRA4 (NM_153692) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC209174L2V
- LentiORF®
Lenti ORF particles, HTRA4 (mGFP-tagged) - Human HtrA serine peptidase 4 (HTRA4), 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | HTRA4 |
Synonyms | FLJ90724 |
Vector | pLenti-C-mGFP |
ACCN | NM_153692 |
ORF Size | 1428 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC209174).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_153692.2, NP_710159.1 |
RefSeq Size | 2130 |
RefSeq ORF | 1431 |
Locus ID | 203100 |
Domains | Tryp_SPc, PDZ, kazal |
Protein Families | Druggable Genome, Protease, Transmembrane |
MW | 51 kDa |
Gene Summary | This gene encodes a member of the HtrA family of proteases. The encoded protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging. [provided by RefSeq, Oct 2008] |
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