beta 3 Adrenergic Receptor (ADRB3) (NM_000025) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC210428L1V

Lenti ORF particles, ADRB3 (Myc-DDK tagged) - Human adrenergic, beta-3-, receptor (ADRB3), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: ADRB3
• Synonyms: BETA3AR
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_000025
• ORF Size: 1224 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC210428).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_000025.1, NP_000016.1
• RefSeq Size: 2660 bp
• RefSeq ORF: 1227 bp
• Locus ID: 155
• Cytogenetics: 8p11.23
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Endocytosis, Neuroactive ligand-receptor interaction
• MW: 43.5 kDa
• Gene Summary: 'The protein encoded by this gene belongs to the family of beta adrenergic receptors, which mediate catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor is located mainly in the adipose tissue and is involved in the regulation of lipolysis and thermogenesis. Obesity and bodyweight-related disorders are correlated with certain polymorphisms in three subtypes of beta-adrenoceptor, among them, the ADRB3 gene.[provided by RefSeq, Oct 2019]'