GABA A Receptor gamma 2 (GABRG2) (NM_000816) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC211528L2V
- LentiORF®
Lenti ORF particles, GABRG2 (mGFP-tagged) - Human gamma-aminobutyric acid (GABA) A receptor, gamma 2 (GABRG2), transcript variant 2, 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | GABRG2 |
Synonyms | CAE2; ECA2; EIEE74; FEB8; GEFSP3 |
Vector | pLenti-C-mGFP |
ACCN | NM_000816 |
ORF Size | 1401 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC211528).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_000816.2, NP_000807.2 |
RefSeq Size | 2370 bp |
RefSeq ORF | 1404 bp |
Locus ID | 2566 |
Cytogenetics | 5q34 |
Domains | Neur_chan_memb, Neur_chan_LBD |
Protein Families | Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane |
Protein Pathways | Neuroactive ligand-receptor interaction |
MW | 54.16 kDa |
Gene Summary | 'This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]' |
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