SP100 (NM_001080391) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC212274L2V
- LentiORF®
Lenti ORF particles, SP100 (mGFP-tagged) - Human SP100 nuclear antigen (SP100), transcript variant 1, 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | SP100 |
Synonyms | lysp100b |
Vector | pLenti-C-mGFP |
ACCN | NM_001080391 |
ORF Size | 2655 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC212274).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001080391.1, NP_001073860.1 |
RefSeq Size | 5455 bp |
RefSeq ORF | 2658 bp |
Locus ID | 6672 |
Cytogenetics | 2q37.1 |
Protein Families | Transcription Factors |
MW | 101.4 kDa |
Gene Summary | 'This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein. [provided by RefSeq, Aug 2011]' |
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