GCN2 (EIF2AK4) (NM_001013703) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC212459L3V

Lenti ORF particles, EIF2AK4 (Myc-DDK tagged) - Human eukaryotic translation initiation factor 2 alpha kinase 4 (EIF2AK4), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: EIF2AK4
• Synonyms: GCN2; PVOD2
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_001013703
• ORF Size: 4947 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC212459).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001013703.2, NP_001013725.2
• RefSeq Size: 5532
• RefSeq ORF: 4950
• Locus ID: 440275
• Protein Families: Druggable Genome, Protein Kinase
• MW: 187.4 kDa
• Gene Summary: This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2. [provided by RefSeq, Mar 2014]