BPNT1 (NM_006085) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC216622L2V

Lenti ORF particles, BPNT1 (mGFP-tagged) - Human 3'(2'), 5'-bisphosphate nucleotidase 1 (BPNT1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: BPNT1
• Synonyms: HEL20; PIP
• Vector: pLenti-C-mGFP
• ACCN: NM_006085
• ORF Size: 924 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC216622).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_006085.4, NP_006076.4
• RefSeq Size: 2461
• RefSeq ORF: 927
• Locus ID: 10380
• Domains: inositol_P
• Protein Pathways: Sulfur metabolism
• MW: 33.2 kDa
• Gene Summary: BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity. [provided by RefSeq, Jul 2008]