HAO1 (NM_017545) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC216834L4V

Lenti ORF particles, HAO1 (mGFP-tagged) - Human hydroxyacid oxidase (glycolate oxidase) 1 (HAO1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: HAO1
• Synonyms: GOX; GOX1; HAOX1
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_017545
• ORF Size: 1110 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC216834).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_017545.2, NP_060015.1
• RefSeq Size: 1746
• RefSeq ORF: 1113
• Locus ID: 54363
• Domains: FMN_dh
• Protein Pathways: Glyoxylate and dicarboxylate metabolism, Metabolic pathways
• MW: 40.9 kDa
• Gene Summary: This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site. [provided by RefSeq, Jul 2008]