Bile Acid Receptor (NR1H4) (NM_005123) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC217443L1V

Lenti ORF particles, Human nuclear receptor subfamily 1, group H, member 4 (NR1H4), transcript variant 2, 200ul, >10^7 TU/mL

Product Images

RC217443L1 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC217443L1V particle to overexpress human NR1H4-Myc-DDK fusion protein.

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  RC217443L1 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC217443L1V particle to overexpress human NR1H4-Myc-DDK fusion protein.

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: Bile Acid Receptor
• Synonyms: BAR; FXR; HRR-1; HRR1; PFIC5; RIP14
• Mammalian Cell Selection: None
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_005123
• ORF Size: 1416 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC217443).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_005123.1
• RefSeq Size: 2218 bp
• RefSeq ORF: 1419 bp
• Locus ID: 9971
• UniProt ID: Q96RI1
• Cytogenetics: 12q23.1
• Domains: HOLI, zf-C4
• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
• MW: 54.2 kDa
• Gene Summary: This gene encodes a ligand-activated transcription factor that shares structural features in common with nuclear hormone receptor family members. This protein functions as a receptor for bile acids, and when bound to bile acids, binds to DNA and regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Feb 2016]