TRIM68 (NM_018073) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC217536L1V

  • LentiORF®

Lenti ORF particles, TRIM68 (Myc-DDK tagged) - Human tripartite motif containing 68 (TRIM68), 200ul, >10^7 TU/mL

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Biosafety Sheet

USD 820.00

3 Weeks*

Size
    • 200 ul
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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Symbol TRIM68
Synonyms GC109; RNF137; SS-56; SS56
Vector pLenti-C-Myc-DDK
ACCN NM_018073
ORF Size 1455 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC217536).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_018073.5, NP_060543.5
RefSeq Size 3321
RefSeq ORF 1458
Locus ID 55128
Domains zf-B_box, RING, SPRY
Protein Families Druggable Genome
MW 56.1 kDa
Gene Summary This gene encodes a member of the tripartite motif-containing protein family, whose members are characterized by a "really interesting new gene" (RING) finger domain, a zinc-binding B-box motif, and a coiled-coil region. Members of this family function as E3 ubiquitin ligases and are involved in a broad range of biological processes. This gene regulates the activation of nuclear receptors, such as androgen receptor, and has been implicated in development of prostate cancer cells, where its expression increases in response to a downregulation of microRNAs. In addition, this gene participates in viral defense regulation as a negative regulator of interferon-beta. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.