SC5DL (SC5D) (NM_006918) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC218412L2V

Lenti ORF particles, SC5D (mGFP-tagged) - Human sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like (SC5DL), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: SC5D
• Synonyms: ERG3; S5DES; SC5DL
• Vector: pLenti-C-mGFP
• ACCN: NM_006918
• ORF Size: 897 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC218412).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_006918.3, NP_008849.2
• RefSeq Size: 2164 bp
• RefSeq ORF: 900 bp
• Locus ID: 6309
• Cytogenetics: 11q23.3-q24.1
• Domains: Sterol_desat
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Metabolic pathways, Steroid biosynthesis
• MW: 35.1 kDa
• Gene Summary: 'This gene encodes an enzyme of cholesterol biosynthesis. The encoded protein catalyzes the conversion of lathosterol into 7-dehydrocholesterol. Mutations in this gene have been associated with lathosterolosis. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]'