Mannosidase II (MAN2A1) (NM_002372) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC220186L4V

Lenti ORF particles, MAN2A1 (mGFP-tagged) - Human mannosidase, alpha, class 2A, member 1 (MAN2A1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: MAN2A1
• Synonyms: AMan II; GOLIM7; MANA2; MANII
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_002372
• ORF Size: 3432 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC220186).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_002372.2, NP_002363.2
• RefSeq Size: 5128 bp
• RefSeq ORF: 3435 bp
• Locus ID: 4124
• Cytogenetics: 5q21.3
• Domains: Glyco_hydro_38
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Metabolic pathways, N-Glycan biosynthesis
• MW: 131 kDa
• Gene Summary: 'This gene encodes a glycosyl hydrolase that localizes to the Golgi and catalyzes the final hydrolytic step in the asparagine-linked oligosaccharide (N-glycan) maturation pathway. Mutations in the mouse homolog of this gene have been shown to cause a systemic autoimmune disease similar to human systemic lupus erythematosus. [provided by RefSeq, Dec 2013]'