RAGE (AGER) (NM_172197) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC220417L3V
- LentiORF®
Lenti ORF particles, AGER (Myc-DDK tagged) - Human advanced glycosylation end product-specific receptor (AGER), transcript variant 7, 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | AGER |
Synonyms | RAGE; SCARJ1 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_172197 |
ORF Size | 1026 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC220417).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_172197.2, NP_751947.1 |
RefSeq Size | 1259 bp |
RefSeq ORF | 1029 bp |
Locus ID | 177 |
Cytogenetics | 6p21.32 |
Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
MW | 34 kDa |
Gene Summary | 'The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847). [provided by RefSeq, May 2011]' |
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