Cytochrome P450 26B (CYP26B1) (NM_019885) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC221075L4V

Lenti ORF particles, CYP26B1 (mGFP-tagged)-Human cytochrome P450, family 26, subfamily B, polypeptide 1 (CYP26B1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: CYP26B1
• Synonyms: CYP26A2; P450RAI-2; P450RAI2; RHFCA
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_019885
• ORF Size: 1536 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC221075).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_019885.3, NP_063938.1
• RefSeq Size: 4567
• RefSeq ORF: 1539
• Locus ID: 56603
• Protein Families: Druggable Genome, P450
• Protein Pathways: Retinol metabolism
• MW: 58 kDa
• Gene Summary: This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]