PTPRD (NM_130391) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC221383L3V
- LentiORF®
Lenti ORF particles, PTPRD (Myc-DDK-tagged)-Human protein tyrosine phosphatase, receptor type, D (PTPRD), transcript variant 2, 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | PTPRD |
Synonyms | HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_130391 |
ORF Size | 4515 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC221383).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_130391.3, NP_569075.2 |
RefSeq Size | 8266 bp |
RefSeq ORF | 4518 bp |
Locus ID | 5789 |
Cytogenetics | 9p24.1-p23 |
Domains | Y_phosphatase, ig, PTPc_motif, IGc2, IG, FN3 |
Protein Families | Druggable Genome, Phosphatase, Transmembrane |
MW | 169.6 kDa |
Gene Summary | 'The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5. [provided by RefSeq, Jan 2010]' |
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