Reelin (RELN) (NM_005045) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC222655L1V

Lenti ORF particles, RELN (Myc-DDK tagged) - Human reelin (RELN), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: RELN
• Synonyms: ETL7; LIS2; PRO1598; RL
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_005045
• ORF Size: 10380 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC222655).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_005045.2, NP_005036.2
• RefSeq Size: 11564 bp
• RefSeq ORF: 10383 bp
• Locus ID: 5649
• Cytogenetics: 7q22.1
• Protein Families: Druggable Genome
• Protein Pathways: ECM-receptor interaction, Focal adhesion
• MW: 388.2 kDa
• Gene Summary: 'This gene encodes a large secreted extracellular matrix protein thought to control cell-cell interactions critical for cell positioning and neuronal migration during brain development. This protein may be involved in schizophrenia, autism, bipolar disorder, major depression and in migration defects associated with temporal lobe epilepsy. Mutations of this gene are associated with autosomal recessive lissencephaly with cerebellar hypoplasia. Two transcript variants encoding distinct isoforms have been identified for this gene. Other transcript variants have been described but their full length nature has not been determined. [provided by RefSeq, Jul 2008]'