CARMIL (CARMIL1) (NM_017640) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC222961L4V

Lenti ORF particles, LRRC16A (mGFP-tagged)-Human leucine rich repeat containing 16A (LRRC16A), transcript variant 1, 200ul, >10^7 TU/mL

Product Images

RC222961L4 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC222961L4V particle to overexpress human CARMIL1-mGFP fusion protein.

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  RC222961L4 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC222961L4V particle to overexpress human CARMIL1-mGFP fusion protein.

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: CARMIL1
• Synonyms: CARMIL; CARMIL1a; dJ501N12.1; dJ501N12.5; LRRC16; LRRC16A
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_017640
• ORF Size: 3978 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC222961).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_017640.6
• RefSeq Size: 5485 bp
• RefSeq ORF: 4116 bp
• Locus ID: 55604
• UniProt ID: Q5VZK9
• Cytogenetics: 6p22.2
• MW: 151.6 kDa
• Gene Summary: Cell membrane-cytoskeleton-associated protein that plays a role in the regulation of actin polymerization at the barbed end of actin filaments. Prevents F-actin heterodimeric capping protein (CP) activity at the leading edges of migrating cells, and hence generates uncapped barbed ends and enhances actin polymerization, however, seems unable to nucleate filaments (PubMed:16054028). Plays a role in lamellipodial protrusion formations and cell migration (PubMed:19846667).[UniProtKB/Swiss-Prot Function]