C1R (NM_001733) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC223007L1V

Lenti ORF particles, C1R (Myc-DDK tagged) - Human complement component 1, r subcomponent (C1R), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: C1R
• Synonyms: EDSPD1
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_001733
• ORF Size: 2115 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC223007).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001733.4, NP_001724.3
• RefSeq Size: 2526 bp
• RefSeq ORF: 2118 bp
• Locus ID: 715
• Cytogenetics: 12p13.31
• Domains: CCP, CUB, Tryp_SPc, EGF_CA, EGF
• Protein Families: Druggable Genome, Protease
• Protein Pathways: Complement and coagulation cascades, Systemic lupus erythematosus
• MW: 80 kDa
• Gene Summary: 'This gene encodes a member of the peptidase S1 protein family. The encoded protein is a proteolytic subunit in the complement system C1 complex. The complement system acts as a mediator in the innate immune response by ultimately triggering phagocytosis, inflammation, and rupturing the bacterial cell wall. Mutations in this gene are associated with Ehlers-Danlos Syndrome. [provided by RefSeq, Dec 2018]'