Dopamine Receptor D3 (DRD3) (NM_000796) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC223426L2V

Lenti ORF particles, DRD3 (mGFP-tagged) - Human dopamine receptor D3 (DRD3), transcript variant a, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: DRD3
• Synonyms: D3DR; ETM1; FET1
• Vector: pLenti-C-mGFP
• ACCN: NM_000796
• ORF Size: 1200 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC223426).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_000796.2, NP_000787.1
• RefSeq Size: 1496 bp
• RefSeq ORF: 1203 bp
• Locus ID: 1814
• Cytogenetics: 3q13.31
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction
• MW: 44 kDa
• Gene Summary: 'This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Jul 2008]'