LIMS1 (NM_001193485) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC231200L1V

Lenti ORF particles, LIMS1 (Myc-DDK tagged) - Human LIM and senescent cell antigen-like domains 1 (LIMS1), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: LIMS1
• Synonyms: PINCH; PINCH-1; PINCH1
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_001193485
• ORF Size: 1161 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC231200).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001193485.1, NP_001180414.1
• RefSeq ORF: 1164 bp
• Locus ID: 3987
• Cytogenetics: 2q12.3
• Protein Families: Druggable Genome
• MW: 44.8 kDa
• Gene Summary: 'The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]'