Tp53 (NM_030989) Rat Tagged ORF Clone Lentiviral Particle
CAT#: RR201296L4V
- LentiORF®
Lenti ORF particles, Tp53 (GFP-tagged ORF) - Rat tumor protein p53 (Tp53), 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Type | Rat Tagged ORF Clone |
Tag | mGFP |
Symbol | Tp53 |
Synonyms | p53; Trp53 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_030989 |
ORF Size | 1173 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RR201296).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_030989.3 |
RefSeq Size | 1792 |
RefSeq ORF | 1176 |
Locus ID | 24842 |
Gene Summary | This gene encodes tumor protein p53, which responds to diverse cellular stresses to regulate target genes that induce cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. p53 protein is expressed at low level in normal cells and at a high level in a variety of transformed cell lines, where it is believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing transcription activation, DNA-binding, and oligomerization domains. It is postulated to bind to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor. Alternatively spliced transcript variants have been found for this gene, but the biological validity of the variants has not been determined. p53 pseudogenes have been found on chromosomes 9 and 18. [provided by RefSeq, Jul 2008] |
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